Evidence map›Paper›PMID 8603882›Full record

ArticleInvestigative ophthalmology & visual science1996

The zebrafish ultraviolet cone opsin reported previously is expressed in rods.

P A Raymond, L K Barthel, D L Stenkamp

Abstract read
PubMed
In one paragraph

Article in Investigative ophthalmology & visual science, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Leveraging Zebrafish to Study Retinal Degenerations.Frontiers in cell and developmental biology · 2018
    Review
  3. Article
  4. Article
  5. Ontogeny of cone photoreceptor mosaics in zebrafish.The Journal of comparative neurology · 2010
    Article
  6. A new form of inherited red-blindness identified in zebrafish.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

P A RaymondDepartment of Anatomy and Cell Biology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.
L K Barthel
D L Stenkamp
University of Michigan–Ann Arbor · US

Funding

NEW NEURONS IN THE RETINAR01EY004318 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAYMOND, PAMELA A · 1985 to 2010
$2.7M
PATTERN FORMATION IN THE VERTEBRATE RETINAF32EY006612 · NEI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI STENKAMP, DEBORAH L · 1994 to 1997
–
NEI NIH HHS F32 EY06612NEI NIH HHS R01 EY04318
6 · The paper itself

Abstract

purposeTo examine expression of the zebrafish ultraviolet cone opsin pigment in goldfish and zebrafish retinas.

methodsDigoxigenin-labeled cRNA probes were prepared by run-off transcription from plasmids containing cDNAs for zebrafish ultraviolet opsin, goldfish ultraviolet cone opsin, and goldfish rod opsin. Probes were hybridized to cryosections of retina and visualized with immunocytochemistry.

resultsThe zebrafish ultraviolet opsin probe hybridized selectively to rod photoreceptors, but not to ultraviolet cones or any other cone type, in both zebrafish and goldfish retinas, and the pattern of expression was identical to that of the goldfish rod opsin probe. The goldfish ultraviolet opsin, in contrast, hybridized to ultraviolet cone photoreceptors in both goldfish and zebrafish.

conclusionsThe cDNA previously identified by Robinson et al as zebrafish ultraviolet opsin is not a cone opsin but is likely to be a rod opsin.

Indexed as

ZebrafishAnimalsBase SequenceDNA, ComplementaryGene ExpressionGoldfishIn Situ HybridizationMolecular Sequence DataRetinal Cone Photoreceptor CellsRetinal Rod Photoreceptor CellsRNA ProbesRod OpsinsUltraviolet RaysDNA, ComplementaryRNA ProbesRod Opsins

Identifiers

PMID8603882
OpenAlexW161248422

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.