ArticleMammalian genome : official journal of the International Mammalian Genome Society1995
Mapping of body weight loci on mouse chromosome X.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 71 citations in OpenAlex.
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- Genetics of Rapid and Extreme Size Evolution in Island Mice.Genetics · 2015Article
- Locally epistatic genomic relationship matrices for genomic association and prediction.Genetics · 2015Article
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- Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross.G3 (Bethesda, Md.) · 2012Article
- A Cmv2 QTL on chromosome X affects MCMV resistance in New Zealand male mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2009Article
- Loci affecting male fertility in hybrids between Mus macedonicus and C57BL/6.Mammalian genome : official journal of the International Mammalian Genome Society · 2004Article
- Loci on chromosomes 2, 4, 9, and 16 for body weight, body length, and adiposity identified in a genome scan of an F2 intercross between the 129P3/J and C57BL/6ByJ mouse strains.Mammalian genome : official journal of the International Mammalian Genome Society · 2003Article
- Mapping of melanoma modifier loci in RET transgenic mice.Japanese journal of cancer research : Gann · 2000Article
- Identification and characterization of proSAAS, a granin-like neuroendocrine peptide precursor that inhibits prohormone processing.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
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- Genetic loci controlling body fat, lipoprotein metabolism, and insulin levels in a multifactorial mouse model.The Journal of clinical investigation · 1998Article
- Congenic strain confirms putative quantitative trait locus for body weight in the rat.Mammalian genome : official journal of the International Mammalian Genome Society · 1998Article
- Developmental quantitative genetics, conditional epigenetic variability and growth in mice.Genetics · 1997Article
- Sensitivity to dietary obesity linked to a locus on chromosome 15 in a CAST/Ei x C57BL/6J F2 intercross.Mammalian genome : official journal of the International Mammalian Genome Society · 1996Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
Inheritance of overweight in humans appears to be under polygenic control. Study on the mouse model may help to determine candidate regions in human genome for the search of overweight genes. Inbred mouse strains showed wide variation in body weight and can provide an experimental model for the study of inheritance of overweight. By genetic linkage analysis, we report the mapping of two loci, named Bw1 and Bw2 (body weight 1 and 2), on Chromosome (Chr) X that strongly affect adult body weight in two interspecific testcross male populations (HSB) and ASB) of mice. In addition, another locus, named Bw3, is also mapped on Chr X in ASB populations. These loci account for up to 24% of the phenotypic variation in both populations. Considering the conserved synteny between mouse and humans Chr X, these results provide candidate regions on Chr X that can be tested for linkage with overweight in humans.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.