Trial reportJournal of epidemiology and community health1995
Improving hypertension control among excessive alcohol drinkers: a randomised controlled trial in France. The WALPA Group.
Trial report in Journal of epidemiology and community health, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Healthcare professional-led interventions on lifestyle modifications for hypertensive patients - a systematic review and meta-analysis.BMC family practice · 2021Pooled it
- Nonpharmacologic Interventions for Reducing Blood Pressure in Adults With Prehypertension to Established Hypertension.Journal of the American Heart Association · 2020Pooled it
- Alcohol intake reduction for controlling hypertension.The Cochrane database of systematic reviews · 2020Pooled it
- 2019 AHA/ACC Clinical Performance and Quality Measures for Adults With High Blood Pressure: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures.Journal of the American College of Cardiology · 2019Guideline
- 2019 AHA/ACC Clinical Performance and Quality Measures for Adults With High Blood Pressure: A Report of the American College of Cardiology/American Heart Association Task Force on Performance Measures.Circulation. Cardiovascular quality and outcomes · 2019Guideline
- 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.Journal of the American College of Cardiology · 2019Guideline
- The effect of a reduction in alcohol consumption on blood pressure: a systematic review and meta-analysis.The Lancet. Public health · 2017Pooled it
- Lifestyle modifications to prevent and control hypertension. 3. Recommendations on alcohol consumption. Canadian Hypertension Society, Canadian Coalition for High Blood Pressure Prevention and Control, Laboratory Centre for Disease Control at Health Canada, Heart and Stroke Foundation of Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 1999Guideline
- A Randomized Trial of Home Blood-Pressure Reduction by Alcohol Guidance During Outpatient Visits: OSAKE Study.American journal of hypertension · 2021Trial
- Effects of Alcohol Reduction Interventions on Blood Pressure.Current hypertension reports · 2022Review
- Association of Alcohol Intake With Hypertension in Type 2 Diabetes Mellitus: The ACCORD Trial.Journal of the American Heart Association · 2020Article
- Review
- 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.Circulation · 2019 · on this mapReview
- 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.Journal of the American College of Cardiology · 2019Article
- Risk factor assessment of stroke and its awareness among stroke survivors: A prospective study.Advanced biomedical research · 2015Article
- Impact of performance improvement continuing medical education on cardiometabolic risk factor control: the COSEHC initiative.The Journal of continuing education in the health professions · 2014Article
- Non-pharmacological aspects of blood pressure management: what are the data?Kidney international · 2011Review
- Short-term outcomes in patients attending a primary care-based addiction shared care program.Canadian family physician Medecin de famille canadien · 2009Article
- Risk estimation for hypertension based on follow-up health examination data in a small village in Kumamoto prefecture, Japan.Environmental health and preventive medicine · 1997Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo improve blood pressure control among hypertensive ( > 140/90 mmHg) excessive alcohol drinkers.
designFourteen worksite physicians were randomised onto an intervention group and a control group. The intervention was based on training the worksite physicians and follow up of those hypertensive subjects defined as excessive drinkers. Follow up was based on self monitoring of alcohol consumption by the subject, in view of the results of their gamma glutamyl transferase (GGT) activity determination.
settingFourteen workplaces in France - mainly in the industrial sector. SUBJECTS: Altogether 15 301 subjects were screened by the 14 physicians: 129 of these were included in the study.
main outcome measuresThis was the difference between the initial systolic blood pressure (SBP) and the SBP one year later (delta BP). Secondary criteria were the difference between the initial and final diastolic blood pressure (delta DBP) and delta BP at two years; antihypertensive treatment; state alcohol consumption (delta AC); delta GGT; and body mass index (delta BMI).
resultsThe decrease in SBP levels was significantly larger in the intervention group than in the control group: at one year, delta SBP values were -11.9 (15.6) mmHg and -4.6 (13.8) respectively (p < 0.05). This benefit was still observed after two years of follow up (-13.8 (17.4) mmHg v -7.5 (14.2) mmHg (p < 0.05)). No difference was observed in DBP. The percentage of treated subjects did not differ between groups. At one year, delta AC was larger in the intervention group (-2.8 (5.2) U/d) than in the control group (-1.6 (3.4) (p < 0.1)). delta GGT and delta BMI did not differ between the two groups. A weak positive correlation was observed between delta AC and delta SBP (r = 0.16).
conclusionAn intervention aimed at the hypertensive excessive drinkers in a working population was found to be effective in reducing SBP on a long term basis (two years). The mechanisms of reduction in alcohol consumption and improved drug compliance cannot be ascertained in this pragmatic study. From a public health point of view, reducing the excess cardiovascular risk among a "hard to reach" population seems feasible with a strategy specifically designed for this high risk group.
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