ArticleBritish journal of cancer1996
Deletion mapping on chromosome 1p in well-differentiated gastric cancer.
Article in British journal of cancer, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 54 citations in OpenAlex.
- Collateral lethality of NAD kinase in 1p36 deleted tumors drives vulnerability to NAD kinase 2 depletion.BBA advances · 2026Article
- miR-495 suppresses osteosarcoma growth and metastasis by directly targeting RUNX3 in the PI3K/Akt pathwayFrontiers in cell and developmental biology · 2026Article
- Chromosomal Instability in Gastric Cancer: Role in Tumor Development, Progression, and Therapy.International journal of molecular sciences · 2023Review
- Review
- UnPAKing RUNX3 functions-Both sides of the coin.Small GTPases · 2019Review
- Detection of genetic alterations in gastric cancer patients from Saudi Arabia using comparative genomic hybridization (CGH).PloS one · 2018Article
- The RUNX family: developmental regulators in cancer.Nature reviews. Cancer · 2015Review
- Stathmin in pancreatic neuroendocrine neoplasms: a marker of proliferation and PI3K signaling.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- The tumor suppressor Chd5 is induced during neuronal differentiation in the developing mouse brain.Gene expression patterns : GEP · 2013Article
- Allelotyping identification of genomic alterations in rectal chromosomally unstable tumors without preoperative treatment.BMC cancer · 2010Article
- Genomic alterations in low-grade, anaplastic astrocytomas and glioblastomas.Pathology oncology research : POR · 2007Article
- Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines.Oncogene · 2004Article
- Chromosomal alterations in paired gastric adenomas and carcinomas.The American journal of pathology · 2001Article
- Allelic loss of the region of chromosome 1p35-pter is associated with progression of human gastric carcinoma.Japanese journal of cancer research : Gann · 2000Article
- Chromosome band 16q24 is frequently deleted in human gastric cancer.British journal of cancer · 1999Article
- Loss of heterozygosity at chromosome 1p in different solid human tumours: association with survival.British journal of cancer · 1999Article
- The structure of the human multiple exostoses 2 gene and characterization of homologs in mouse and Caenorhabditis elegans.Genome research · 1997Article
- Commonly deleted region on the long arm of chromosome 7 in differentiated adenocarcinoma of the stomach.British journal of cancer · 1997Article
- The Rhesus D-negative phenotype is an independent predictor of poor prognosis in curatively (RO) resected gastric cancer patients.British journal of cancer · 1997Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To define the region on the short arm of chromosome 1 that is thought to include one or more tumour-suppressor genes for gastric cancers, we carried out loss of heterozygosity (LOH) studies in 26 gastric adenocarcinomas, using three restriction fragment length polymorphism (RFLP) markers and nine microsatellite markers. All tumours were informative with at least one locus; three revealed replication errors (RERs) at multiple microsatellite loci, and interstitial or telomeric allelic deletions were observed in 12 cases. Deletion mapping of these tumours defined a commonly deleted region between two loci, D1S201 and D1S197, that are 13 cM apart. As two loci within the commonly deleted region, D1S57 (pYNZ2) and D1S62 (pTHI54), were mapped respectively to 1p35 and 1p34.3 by fluorescence in situ hybridisation, we conclude that a locus likely to contain a tumour-suppressor gene for gastric cancer is located within a 13 cM region encompassing two chromosomal bands.
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