Evidence map›Paper›PMID 8594573›Full record

ArticleNucleic acids research1996

A general database for DNA sequence changes induced by mutagenesis of several bacterial and mammalian genes.

F Hutchinson, J E Donnellan

Open access · bronzeAbstract read
In one paragraph

Article in Nucleic acids research, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

F HutchinsonDepartment of Therapeutic Radiology, Yale University School of Medicine, New Have, CT 06520-8040, USA.
J E Donnellan
Yale University · US

Funding

DNA SEQUENCE CHANGES INDUCED BY MUTAGENSR01CA058952 · NCI · YALE UNIVERSITY · PI SUMMERS, WILLIAM C · 1993 to 1998
–
NCI NIH HHS CA58952
6 · The paper itself

Abstract

This electronic database is a collection of 225 sets of data on mutations in more than twenty-three thousand mutants (October, 1995) in eleven bacterial genes, five mammalian genes and one gene in yeast cells. Each dataset consists of the changes in DNA sequence in the mutants, typically tens to hundreds, induced by mutagenesis of a particular cell line under specific conditions. The database is available on the Internet and on diskettes, and is periodically updated. Researchers are invited to submit additional data. A data entry program, MUTSIN, is available that diagrams each mutation on the computer screen as entered and alerts the user to any inconsistency between the entry and the wild type gene sequence.

Indexed as

Databases, FactualGenes, BacterialMutagenesisAnimalsBase SequenceComputer Communication NetworksDNAEscherichia coliHumansMammalsMolecular Sequence DataSaccharomyces cerevisiaeDNA

Identifiers

PMID8594573
PMCPMC145591
OpenAlexW1996300100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.