Evidence map›Paper›PMID 8590597›Full record

ArticleJournal of protein chemistry1995

Adenosine dialdehyde blocks the disappearance of two nerve growth factor-induced insoluble proteins.

J Y VanDenburg, P N McFadden

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of protein chemistry, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

J Y VanDenburgDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis 97331, USA.
P N McFadden
Oregon State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two nonionic-detergent-insoluble proteins are induced early in the nerve growth factor (NGF)-induced neuronal differentiation of PC12 cells. The pools of these two proteins then disappear from the insoluble fraction after a few days of continued exposure of the cells to NGF. The methylation-inhibiting drug adenosine dialdehyde blocks the disappearance of these insoluble proteins, implicating a methylation-dependent step in the pathway that regulates the fate of these proteins.

Indexed as

AdenosineAnimalsAntimetabolitesCell DifferentiationNeoplasm ProteinsNerve Growth FactorsPC12 CellsRatsSolubilityAdenosineAntimetabolitesNeoplasm ProteinsNerve Growth Factorsperiodate-oxidized adenosine

Identifiers

PMID8590597
OpenAlexW2055004857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.