Evidence map›Paper›PMID 8586726›Full record

Trial reportJournal of clinical microbiology1995

PCR detection of cytomegalovirus DNA in serum as a diagnostic test for congenital cytomegalovirus infection.

C T Nelson, A S Istas, M K Wilkerson, G J Demmler

Open access · bronzeAbstract readClinical TrialControlled Clinical Trial
In one paragraph

Trial report in Journal of clinical microbiology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 80 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Diagnosis of congenital cytomegalovirus infection in high risk neonates.Mediterranean journal of hematology and infectious diseases · 2013
    Article
  8. Overview of the diagnosis of cytomegalovirus infection.Infectious disorders drug targets · 2011
    Article
  9. Cytomegalovirus-specific, high-avidity IgG with neutralizing activity in maternal circulation enriched in the fetal bloodstream.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2009
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

C T NelsonDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
A S Istas
M K Wilkerson
G J Demmler
Baylor College of Medicine · US

Funding

UNDERSTANDING FXTAS AMONG MALES WITH THE FMR1 PREMUTATIONP30HD024064 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI TOLIAS, KIMBERLY R · 1988 to 2013
$29.4M
NICHD NIH HHS 2P30 HD24064PHS HHS M01-00188
6 · The paper itself

Abstract

PCR detected cytomegalovirus (CMV) DNA in the serum of 18 of 18 infants with symptomatic congenital CMV infection, 1 of 2 infants with asymptomatic congenital CMV infection, and 0 of 32 controls. Serum CMV PCR provided a rapid, sensitive, and specific method for diagnosis of congenital CMV infection in infants who were symptomatic at birth.

Indexed as

Antibodies, ViralCytomegalovirusCytomegalovirus InfectionsDNA, ViralFemaleHumansImmunoglobulin MInfant, NewbornMalePolymerase Chain ReactionSensitivity and SpecificityUrineAntibodies, ViralDNA, ViralImmunoglobulin M

Identifiers

PMID8586726
PMCPMC228697
OpenAlexW2137362774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.