ArticleJournal of clinical microbiology1995
Nosocomial outbreak caused by Scedosporium prolificans (inflatum): four fatal cases in leukemic patients.
Article in Journal of clinical microbiology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 97 citations in OpenAlex.
- Computational design of an mRNA vaccine targeting antifungal-resistant Lomentospora prolificans.Scientific reports · 2025Article
- EarlyIDCases · 2025Article
- Scedosporiosis and lomentosporiosis: modern perspectives on these difficult-to-treat rare mold infections.Clinical microbiology reviews · 2024Review
- Outbreaks of Fungal Infections in Hospitals: Epidemiology, Detection, and Management.Journal of fungi (Basel, Switzerland) · 2023Review
- Non-Journal of fungi (Basel, Switzerland) · 2023Review
- What's New in Prevention of Invasive Fungal Diseases during Hospital Construction and Renovation Work: An Overview.Journal of fungi (Basel, Switzerland) · 2023Review
- Review
- Dual fungal infection withClinical case reports · 2021Article
- Investigation of aMedical mycology case reports · 2020Article
- Article
- Conidial germination in Scedosporium apiospermum, S. aurantiacum, S. minutisporum and Lomentospora prolificans: influence of growth conditions and antifungal susceptibility profiles.Memorias do Instituto Oswaldo Cruz · 2016Article
- Targeted Disruption of Melanin Biosynthesis Genes in the Human Pathogenic Fungus Lomentospora prolificans and Its Consequences for Pathogen Survival.International journal of molecular sciences · 2016Article
- Could Histoplasma capsulatum Be Related to Healthcare-Associated Infections?BioMed research international · 2015Review
- Melanized fungi in human disease.Clinical microbiology reviews · 2010Review
- Molecular typing of Australian Scedosporium isolates showing genetic variability and numerous S. aurantiacum.Emerging infectious diseases · 2008Article
- Infections caused by Scedosporium spp.Clinical microbiology reviews · 2008Review
- Caspofungin and liposomal amphotericin B therapy of experimental murine scedosporiosis.Antimicrobial agents and chemotherapy · 2005Article
- Outbreaks of infectious diseases in stem cell transplant units: a silent cause of death for patients and transplant programmes.Bone marrow transplantation · 2004Article
- In vitro activities of new and conventional antifungal agents against clinical Scedosporium isolates.Antimicrobial agents and chemotherapy · 2002Article
- Disseminated infection caused by Scedosporium prolificans in a patient with acute multilineal leukemia.Journal of clinical microbiology · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Four cases of fatal disseminated Scedosporium prolificans (inflatum) infection occurring in neutropenic patients are reported. Because of hospital renovation, the patients were cared for in a temporary hematologic facility. S. prolificans (inflatum) was isolated from blood cultures of these four patients, two of whom underwent full necropsy, and revealed abundant vegetative hyphae and ovoid conida with truncate bases in many organs. In vitro susceptibility testing of fungal strains showed all isolates to be resistant to amphotericin B, flucytosine, miconazole, ketoconazole, fluconazole, and itraconazole, with MICs greater than 16 micrograms/ml. The reported infections, two in each of two rooms, occurred over a period of 1 month, with very similar clinical outcomes. Circumstancial evidence suggested a nosocomial outbreak, but the environmental samples collected from the rooms, corridors, and adjacent areas did not yield S. prolificans (inflatum). Nevertheless, circumstantial evidence suggested a nosocomial outbreak of S. prolificans (inflatum) infection.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.