ArticleEuropean biophysics journal : EBJ1995
Pores formed in lipid bilayers and in native membranes by nodularin, a cyanobacterial toxin.
Article in European biophysics journal : EBJ, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 21 citations in OpenAlex.
- Differential Labeling of Chemically Modified Peptides and Lipids among CyanobacteriaMicroorganisms · 2021Article
- Chemically labeled toxins or bioactive peptides show a heterogeneous intracellular distribution and low spatial overlap with autofluorescence in bloom-forming cyanobacteria.Scientific reports · 2020Article
- Lipid-Detergent Phase Transitions During Detergent-Mediated Liposome Solubilization.The Journal of membrane biology · 2016Article
- Impact of inorganic carbon availability on microcystin production by Microcystis aeruginosa PCC 7806.Applied and environmental microbiology · 2007Article
- Membrane packing geometry of diphytanoylphosphatidylcholine is highly sensitive to hydration: phospholipid polymorphism induced by molecular rearrangement in the headgroup region.Biophysical journal · 1997Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nodularin (NODLN), a cyclic pentapeptide hepatotoxin from the cyanobacterium Nodularia spumigena, induces pores in bilayers of diphytanoyl lecithin (DPhL) and in locust muscle membrane. NODLN increases the surface pressure of a DPhL monolayer; except when the surface pressure of the monolayer is high when the toxin causes a reduction of this parameter. NODLN pores exhibit many open conductance states; the higher state probabilities increasing when the transmembrane pressure is increased. The results from these studies are discussed in terms of two models for a NODLN pore, a torroidal model and a barrel-stave model. The edge energy of the NODLN pore of 1.4 x 10(-12) J/m is determined.
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Registered trials
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