ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology1995
Impact of rearrangements on function and position of chromosomes in the interphase nucleus and on human genetic disorders.
Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Donor Y chromosome in renal carcinoma cells of a female BMT recipient: visualization of putative BMT-tumor hybrids by FISH.Bone marrow transplantation · 2005Article
- The detection of t(14;18) in archival lymph nodes: development of a fluorescence in situ hybridization (FISH)-based method and evaluation by comparison with polymerase chain reaction.The Journal of molecular diagnostics : JMD · 2003Article
- Principles of the highly ordered arrangement of metaphase I bivalents in spermatocytes of Agrodiaetus (Insecta, Lepidoptera).Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2002Article
- Replication status as a possible marker for genomic instability in cells originating from genotypes with balanced rearrangements.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2001Article
- Chromosomal painting detects non-random chromosome arrangement in dasyurid marsupial sperm.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2001Article
- Differences in the localization and morphology of chromosomes in the human nucleus.The Journal of cell biology · 1999Article
- Molecular cloning of the human UMP synthase gene and characterization of point mutations in two hereditary orotic aciduria families.American journal of human genetics · 1997Article
- Clonal analysis of delayed karyotypic abnormalities and gene mutations in radiation-induced genetic instability.Molecular and cellular biology · 1996Article
- Ordered tandem arrangement of chromosomes in the sperm heads of monotreme mammals.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- A case of duplication of 13q32-->qter and deletion of 18p11.32-->pter with mild phenotype: Patau syndrome and duplications of 13q revisited.Journal of medical genetics · 1996Article
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A synthesis of numerous published data and my own observations reveal that chromatin structure in interphase is functional, dynamic and complex. I hypothesize that: (1) chromosome regions organize nuclear structures and thus their own environment (address themselves in sites and condensation patterns most appropriate for their functional state in the particular cell); (2) chromosome rearrangement could alter nuclear architecture and thus function; and (3) these ideas can explain the contribution of chromosome rearrangements, even in a balanced form, to human pathologic conditions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.