ArticleJournal of molecular evolution1996
Computer simulation of transposable element evolution: random template and strict master models.
Article in Journal of molecular evolution, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Impact of a horizontally transferred Helitron family on genome evolution in Xenopus laevis.Mobile DNA · 2025Article
- Accuracy of multiple sequence alignment methods in the reconstruction of transposable element families.NAR genomics and bioinformatics · 2022Article
- Flying Around in the Genome: Characterization of LINE-1 in Chiroptera.Special publications (Texas Tech University. Museum) · 2019Article
- Origin and recent expansion of an endogenous gammaretroviral lineage in domestic and wild canids.Retrovirology · 2019Article
- Article
- LINEs between Species: Evolutionary Dynamics of LINE-1 Retrotransposons across the Eukaryotic Tree of Life.Genome biology and evolution · 2016Article
- Evolutionary dynamics of selfish DNA explains the abundance distribution of genomic subsequences.Scientific reports · 2016Article
- Reconstructing the evolutionary history of gypsy retrotransposons in the Périgord black truffle (Tuber melanosporum Vittad.).Mycorrhiza · 2016Article
- Computational Evaluation of the Strict Master and Random Template Models of Endogenous Retrovirus Evolution.PloS one · 2016Article
- Reviving the dead: history and reactivation of an extinct l1.PLoS genetics · 2014Article
- Reconstructing the evolutionary history of transposable elements.Genome biology and evolution · 2013Article
- The first sequenced carnivore genome shows complex host-endogenous retrovirus relationships.PloS one · 2011Article
- Bursts and horizontal evolution of DNA transposons in the speciation of pseudotetraploid salmonids.BMC genomics · 2007Article
- The evolution of mobile DNAs: when will transposons create phylogenies that look as if there is a master gene?Genetics · 2006Article
- Paleogenomic record of the extinction of human endogenous retrovirus ERV9.Journal of virology · 2005Article
- Long-term reinfection of the human genome by endogenous retroviruses.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
- Different rates of LINE-1 (L1) retrotransposon amplification and evolution in New World monkeys.Journal of molecular evolution · 2004Article
- Evolutionary course of CsRn1 long-terminal-repeat retrotransposon and its heterogeneous integrations into the genome of the liver fluke, Clonorchis sinensis.The Korean journal of parasitology · 2003Article
- Genomic demography: a life-history analysis of transposable element evolution.Proceedings. Biological sciences · 1999Article
- Molecular evolution of two lineages of L1 (LINE-1) retrotransposons in the california mouse, Peromyscus californicus.Genetics · 1998Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
It has been proposed that the most extensively studied mammalian retrotransposons replicate by some form of a master template model. This conclusion has been drawn largely from DNA sequence analysis and is based on phylogenetic tree topology, the presence and ordering of shared variants, the degree of divergence between elements within a subfamily, and the shape of the distribution of pairwise differences between elements. To investigate how robust these parameters are as predictors of the model of transposition, computer simulations of the two most extreme transposition models, the Random Template Model and the Strict Master Model, were carried out. A prototype of a computer simulator for studying retrotransposition is presented. The simulator is a versatile digital workbench that maintains DNA sequence data and allows manipulation of a range of factors including reverse transcriptase and in situ mutation rates, transposition template, and transposition rate. All parameters previously used as predictors of the model of transposition were markedly different for the two extreme models when evaluated using large sample sizes of sequences from experiments simulating up to 15 million years of evolution.
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