Evidence map›Paper›PMID 8576959›Full record

ArticleJournal of molecular evolution1996

Genetic variation of recent Alu insertions in human populations.

M A Batzer, S S Arcot, J W Phinney, M Alegria-Hartman, D H Kass, S M Milligan, C Kimpton, P Gill, M Hochmeister, P A Ioannou and 6 more

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular evolution, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005236 (Atherosclerosis and Omega-3 Fatty Acids in Alaskan Natives), which is not on this map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00005236 completednot on this map

Atherosclerosis and Omega-3 Fatty Acids in Alaskan Natives

TypeobservationalSponsorNational Heart, Lung, and Blood Institute (NHLBI)Ran1988 to 1994ConditionsCardiovascular Diseases, Heart Diseases, Atherosclerosis, Coronary Arteriosclerosis
3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 209 citations in OpenAlex.

  1. Review
  2. AnNAR genomics and bioinformatics · 2022
    Article
  3. Article
  4. Article
  5. Review
  6. Article
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  9. Article
  10. The role of transposable elements in health and diseases of the central nervous system.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013
    Review
  11. Laboratory methods for the analysis of primate mobile elements.Methods in molecular biology (Clifton, N.J.) · 2010
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
  19. Tracking Alu evolution in New World primates.BMC evolutionary biology · 2005
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 4 countries.

M A BatzerHuman Genome Center, Lawrence Livermore National Laboratory, CA 94551, USA.
S S Arcot
J W Phinney
M Alegria-Hartman
D H Kass
S M Milligan
C Kimpton
P Gill
M Hochmeister
P A Ioannou
R J Herrera
D A Boudreau
W D Scheer
B J Keats
P L Deininger
M Stoneking
Lawrence Livermore National Laboratory · USLouisiana State University · USThe Priory Hospital · GBUniversity Medical Center New Orleans · USCyprus Institute of Neurology and Genetics · CYFlorida International University · USMichigan State Police · USPennsylvania State University · USUniversity of Bern · CH

Funding

HUMAN-SPECIFIC ALU-SEQUENCE TAGGED SITESR01HG000770 · NHGRI · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI DEININGER, PRESCOTT L · 1993 to 1995
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ATHEROSCLEROSIS &W-3 FATTY ACIDS IN ALASKAN NATIVESR01HL042082 · NHLBI · LOUISIANA STATE UNIV HSC NEW ORLEANS · PI NEWMAN, WILLIAM P · 1989 to 1993
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STRUCTURAL STUDIES OF HUMAN LACTOFERRINS06RR008205 · NCRR · FLORIDA INTERNATIONAL UNIVERSITY · PI BONE, RICHARD A · 1985 to 1989
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NCRR NIH HHS RR 08205NHGRI NIH HHS R01 HG 00770NHLBI NIH HHS HL-42082
6 · The paper itself

Abstract

The Alu family of interspersed repeats is comprised of over 500,000 members which may be divided into discrete subfamilies based upon mutations held in common between members. Distinct subfamilies of Alu sequences have amplified within the human genome in recent evolutionary history. Several individual Alu family members have amplified so recently in human evolution that they are variable as to presence and absence at specific loci within different human populations. Here, we report on the distribution of six polymorphic Alu insertions in a survey of 563 individuals from 14 human population groups across several continents. Our results indicate that these polymorphic Alu insertions probably have an African origin and that there is a much smaller amount of genetic variation between European populations than that found between other population groups.

Indexed as

Genetic VariationBase SequenceBiological EvolutionHumansMolecular Sequence DataPolymorphism, GeneticRacial GroupsRepetitive Sequences, Nucleic Acid

Identifiers

PMID8576959
OpenAlexW2097559754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.