ArticleThe Journal of physiology1995
A study of the role of corticosterone as a mediator in exercise-induced stimulation of murine macrophage phagocytosis.
Article in The Journal of physiology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 61 citations in OpenAlex.
- Exercise-induced anxiety impairs local and systemic inflammatory response and glucose metabolism in C57BL/6J mice.Brain, behavior, & immunity - health · 2025Article
- Effect of mud-bath therapy on the innate/inflammatory responses in elderly patients with osteoarthritis: a discussion of recent results and a pilot study on the role of the innate function of monocytes.International journal of biometeorology · 2020Article
- The "bioregulatory effect of exercise" on the innate/inflammatory responses.Journal of physiology and biochemistry · 2016Review
- Influence of exercise on NA- and Hsp72-induced release of IFNγ by the peritoneal suspension of macrophages and lymphocytes from genetically obese Zucker rats.Journal of physiology and biochemistry · 2013Article
- Differential effects of acute (extenuating) and chronic (training) exercise on inflammation and oxidative stress status in an animal model of type 2 diabetes mellitus.Mediators of inflammation · 2011Article
- Exercise-induced extracellular 72 kDa heat shock protein (Hsp72) stimulates neutrophil phagocytic and fungicidal capacities via TLR-2.European journal of applied physiology · 2010Article
- Phagocytic responses of peritoneal macrophages and neutrophils are different in rats following prolonged exercise.Clinics (Sao Paulo, Brazil) · 2010Article
- Influence of exercise on the circulating levels and macrophage production of IL-1beta and IFNgamma affected by metabolic syndrome: an obese Zucker rat experimental animal model.European journal of applied physiology · 2009Article
- Effect of exercise on glutamine metabolism in macrophages of trained rats.European journal of applied physiology · 2009Article
- Brain-immune interactions and disease susceptibility.Molecular psychiatry · 2005Review
- Norepinephrine as mediator in the stimulation of phagocytosis induced by moderate exercise.European journal of applied physiology · 2005Article
- Effect of orally administered L-tryptophan on serotonin, melatonin, and the innate immune response in the rat.Molecular and cellular biochemistry · 2004Article
- Enhanced chemotaxis of macrophages by strenuous exercise in trained mice: thyroid hormones as possible mediators.Molecular and cellular biochemistry · 1999Article
- Effect of polar glycopeptidolipids from Mycobacterium chelonae (GPLp-Mc) on phagocytosis and superoxide anion production of macrophages from mice. Influence of physical activity.Molecular and cellular biochemistry · 1998Article
- Exercise-induced stimulation of murine macrophage chemotaxis: role of corticosterone and prolactin as mediators.The Journal of physiology · 1997Article
- Article
- Exercise Induced Alterations in Rat Monocyte Number, Morphology, and Function.International journal of exercise scienceArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. It is generally accepted that physical activity provokes changes in the immune system. Previous studies have demonstrated that the stress of physical activity (swimming until exhaustion) increases the phagocytic activity of peritoneal macrophages. However, the precise mechanisms remain unknown. 2. Two experiments were performed in the present study. (A) Peritoneal macrophages from control mice were incubated with plasma from three different groups of mice: (1) mice subjected to swimming until exhaustion with no previous training, (2) mice subjected to the same activity but with 1 month of training (30 min day-1), and (3) a control (non-exercised) group. The differences in the resulting phagocytic (attachment and ingestion) capacity were measured. (B) Changes in the concentration of plasma corticosterone after exercise were also measured, and the effect of incubation with the postexercise plasma corticosterone level on the phagocytic activity of peritoneal macrophages was then studied in vitro. 3. The results were: (A) incubation with plasma from both groups of exercised mice (with and without previous training) led to increased levels of phagocytic capacity (number of C. albicans cells ingested per 100 macrophages). (B) Incubation with a corticosterone concentration of 0.72 mumol l-1 (similar to that observed in plasma immediately after exercise) raised the phagocytic capacity (144 +/- 12 after incubation with 0.72 mumol l-1 vs. 93 +/- 19 after incubation with 0.24 mumol l-1). This increase was also significantly greater than that observed with 7.2 mumol l-1 corticosterone. 4. It is concluded that corticosterone may mediate the increased phagocytic function of peritoneal macrophages induced by exercise.
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