ArticleJournal of clinical microbiology1995
Molecular subtyping of prevalent M serotypes of Streptococcus pyogenes causing invasive disease.
Article in Journal of clinical microbiology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 73 citations in OpenAlex.
- IncHI1 plasmids are epidemic vectors that mediate transmission ofFrontiers in microbiology · 2023Article
- Characterization of Streptococcus pyogenes from Animal Clinical Specimens, Spain.Emerging infectious diseases · 2017Article
- Molecular characterization and evaluation of the emerging antibiotic-resistant Streptococcus pyogenes from eastern India.BMC infectious diseases · 2016Article
- Genome sequence and virulence factors of a group G Streptococcus dysgalactiae subsp. equisimilis strain with a new element carrying erm(B).Scientific reports · 2016Article
- Vigilant keratinocytes trigger pathogen-associated molecular pattern signaling in response to streptococcal M1 protein.Infection and immunity · 2015Article
- Subtyping of emm1 group A Streptococci causing invasive infections in France.Journal of clinical microbiology · 2009Article
- Rapid emergence of emm84 among invasive Streptococcus pyogenes infections in Finland.Journal of clinical microbiology · 2009Article
- Group A streptococci from invasive-disease episodes in Poland are remarkably divergent at the molecular level.Journal of clinical microbiology · 2006Article
- M protein typing of Thai group A streptococcal isolates by PCR-Restriction fragment length polymorphism analysis.BMC microbiology · 2005Article
- Epidemiology and molecular characterization of Streptococcus pyogenes recovered from scarlet fever patients in central Taiwan from 1996 to 1999.Journal of clinical microbiology · 2004Article
- Survey of emm gene sequences from pharyngeal Streptococcus pyogenes isolates collected in Spain and their relationship with erythromycin susceptibility.Journal of clinical microbiology · 2003Article
- Epidemiologic analysis of invasive and noninvasive group a streptococcal isolates in Hong Kong.Journal of clinical microbiology · 2003Article
- High rate of tetracycline resistance in Streptococcus pyogenes in Iran: an epidemiological study.Journal of clinical microbiology · 2000Article
- Genetic relatedness and superantigen expression in group A streptococcus serotype M1 isolates from patients with severe and nonsevere invasive diseases.Infection and immunity · 2000Article
- Characteristics of Streptococcus pyogenes serotype M1 and M3 isolates from patients in Japan from 1981 to 1997.Journal of clinical microbiology · 1999Article
- Invasive and noninvasive group A streptococcal isolates with different speA alleles in The Netherlands: genetic relatedness and production of pyrogenic exotoxins A and B.Journal of clinical microbiology · 1999Article
- High-resolution genotyping of Streptococcus pyogenes serotype M1 isolates by fluorescent amplified-fragment length polymorphism analysis.Journal of clinical microbiology · 1999Article
- Relatedness of Streptococcus canis from canine streptococcal toxic shock syndrome and necrotizing fasciitis.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 1999Article
- Fluorescent amplified-fragment length polymorphism analysis of an outbreak of group A streptococcal invasive disease.Journal of clinical microbiology · 1998Article
- Genotyping of outbreak-related and sporadic isolates of Clostridium difficile belonging to serogroup C.Journal of clinical microbiology · 1996Article
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Authors and funding
5 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reproducible methodologies and a scheme for high-resolution genotyping of Streptococcus pyogenes were defined with respect to a study of six predominant M serotypes causing invasive group A streptococcal disease in the United Kingdom. Serotype reference strains were compared with nine clinical isolates of each serotype from patients with diseases such as pneumonia, puerperal sepsis, toxic shock-like-syndrome, cellulitis, or necrotizing fasciitis. Four enzymes were evaluated for their discriminatory power in 16S rRNA gene-specific ribotyping. Discriminatory power was greatest with EcoRI, which generated serotype-specific ribotypes, and with SacI, which could subdivide strains of the same M serotype. Twenty-five combined ribotypes were found among the 60 strains, and the indices of discriminatory power (D values) of this method varied from 0.51 within serotype M1 to 0.98 within strains of serotype M5. Macrorestriction with the rarely cutting endonuclease SmaI and pulsed-field gel electrophoresis gave D values varying from 0.37 within serotype M1 to the maximal 1.0 within serotype M5. Comparison of macrorestriction profiles revealed various degrees of genetic heterogeneity within M serotypes. Strains of M1, M3, M6, and M11 exhibited clonally related macrorestriction profiles, while those of R28 and M5 strains were consistent with polyphyletic origin.
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