ReviewThe Histochemical journal1995
Histochemistry of nitric oxide synthase in the nervous system.
Review in The Histochemical journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 127 citations in OpenAlex.
- Shades of gray in human white matter.The Journal of comparative neurology · 2023Article
- Article
- Nitric Oxide and the Neuroendocrine Control of the Osmotic Stress Response in Teleosts.International journal of molecular sciences · 2019Review
- Periaqueductal gray neuroplasticity following chronic morphine varies with age: role of oxidative stress.Neuroscience · 2012Article
- Neuroplastic and neuropathological changes in the central nervous system of the Gray mussel Crenomytilus grayanus (Dunker) under environmental stress.Invertebrate neuroscience : IN · 2010Article
- Nitric Oxide Synthase Inhibitors as Antidepressants.Pharmaceuticals (Basel, Switzerland) · 2010Review
- Nitric oxide synthase activity and expression are decreased in the paraventricular nucleus of pregnant rats.Brain research · 2009Article
- Age-related changes of NADPH-diaphorase positivity in the rat rostral migratory stream.Cellular and molecular neurobiology · 2005Article
- Regulation of neuronal proliferation and differentiation by nitric oxide.Molecular neurobiology · 2003Review
- Nitric oxide is an essential negative regulator of cell proliferation in Xenopus brain.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Ultrastructural localisation of NADPH-d/nNOS expression in the superior cervical ganglion of the hamster.Journal of anatomy · 2000Article
- Skeletal muscle fibres show NADPH diaphorase activity associated with mitochondria, the sarcoplasmic reticulum and the NOS-1-containing sarcolemma.The Histochemical journal · 2000Article
- Nitric oxide influences injury-induced microglial migration and accumulation in the leech CNS.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2000Article
- Nitric oxide stimulates ACTH secretion and the transcription of the genes encoding for NGFI-B, corticotropin-releasing factor, corticotropin-releasing factor receptor type 1, and vasopressin in the hypothalamus of the intact rat.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1999Article
- Injury-induced expression of endothelial nitric oxide synthase by glial and microglial cells in the leech central nervous system within minutes after injury.Proceedings. Biological sciences · 1998Article
- Histochemical differentiation between nitric oxide synthase-related and -unrelated diaphorase activity in the rat olfactory bulb.The Histochemical journal · 1998Article
- Nitric oxide synthase immunoreactive nerves in rat and ferret salivary glands, and effects of denervation.The Histochemical journal · 1997Article
- Species-independent expression of nitric oxide synthase in the sarcolemma region of visceral and somatic striated muscle fibers.Cell and tissue research · 1995Article
- The number of proliferating cells in the rostral migratory stream of rat during the first postnatal month.Cellular and molecular neurobiologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nitric oxide synthase, which generates the physiological messenger molecule nitric oxide, and its associated NADPH diaphorase (NADPHd) activity are distributed throughout selective neuronal populations of the central and peripheral nervous system. Considerable evidence has been accumulated to indicate that NADPHd activity labels cells lacking neuronal nitric oxide synthase, i.e., the specificity of the reaction has to be considered for the reliable detection of the enzyme in neuronal but also non-neuronal tissue. In the present review, critical aspects of nitric oxide synthase visualization in neurones, using its NADPHd activity, are discussed. Furthermore, the organization of the central and peripheral nitric oxide synthase-containing neuronal systems is described. Nitric oxide synthase is present in local cortical and striatal neurones, hypothalamic magnocellular neurones, mesopontine cholinergic neurones, cerebellar interneurones, preganglionic sympathetic and parasympathetic neurones, neurones in parasympathetic autonomic and enteric ganglia and primary viscero-afferent neurones. Finally, injury-related alterations in nitric oxide synthase activity are briefly outlined. In this respect, the histochemistry of nitric oxide synthase may represent a valuable marker for neurochemical, if not structural, alterations observed in neural diseases, regeneration and transplantation.
Indexed as
Identifiers
8575942W2026071721What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.