Evidence map›Paper›PMID 8575815›Full record

ArticleImmunogenetics1996

Physical map of the HLA-A/HLA-F subregion and identification of two new coding sequences.

L Pichon, T Giffon, B Chauvel, G Carn, P Bouric, A El Kahloun, J Y Legall, V David

Abstract read
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In one paragraph

Article in Immunogenetics, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

L PichonDepartment of Biochemistry and Molecular Biology, UPR 41 CNRS - "Recombinaisons génétiques" Faculté de Médecine, 2 avenue du Professeur Léon Bernard, 35043 Rennes Cedex, France.
T Giffon
B Chauvel
G Carn
P Bouric
A El Kahloun
J Y Legall
V David

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As part of an effort to characterize the hemochromatosis gene, we selected three non-chimeric yeast artificial chromosomes (YACs) overlapping with the YAC B30 previously described and forming an 800 kilobase contig covering the HLA-A/HLA-F region. The precise physical map of these YACs and of the corresponding genomic region were established. Nine concentrated sites of CpG cutter elements, potentially HTF islands, were mapped. In addition, several probes have been generated as tools for mapping and examining transcripts produced in the region. This allowed for the characterization and localization of two new coding sequences, provisionally named HCG (for hemochromatosis candidate gene) and numbered VIII and IX.

Indexed as

Chromosomes, Human, Pair 6Open Reading FramesRestriction MappingBlotting, NorthernChromosomes, Artificial, YeastCloning, MolecularDNA, ComplementaryDNA FingerprintingElectrophoresis, Gel, Pulsed-FieldGene LibraryHemochromatosisHistocompatibility Antigens Class IHLA-A AntigensHLA AntigensHumansMolecular Sequence DataDNA, ComplementaryHistocompatibility Antigens Class IHLA-A AntigensHLA AntigensHLA-F antigensPOLR1HASP protein, human

Identifiers

PMID8575815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.