ArticleCurrent genetics1995
A two-reporter gene system for the analysis of bi-directional transcription from the divergent MAL6T-MAL6S promoter in Saccharomyces cerevisiae.
Article in Current genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- Suppression of expression between adjacent genes within heterologous modules in yeast.G3 (Bethesda, Md.) · 2014Article
- Carbon source dependent promoters in yeasts.Microbial cell factories · 2014Review
- Bi-directional duplex promoters with duplicated enhancers significantly increase transgene expression in grape and tobacco.Transgenic research · 2004Article
- Direct correlation between positron emission tomographic images of two reporter genes delivered by two distinct adenoviral vectors.Gene therapy · 2001Article
- Genetic evidence that high noninduced maltase and maltose permease activities, governed by MALx3-encoded transcriptional regulators, determine efficiency of gas production by baker's yeast in unsugared dough.Applied and environmental microbiology · 1999Article
- A flow cytometric method for rapid selection of novel industrial yeast hybrids.Applied and environmental microbiology · 1998Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many sets of genes in Saccharomyces cerevisiae are divergently transcribed, but at present there are no vectors generally available for the simultaneous analysis of divergent transcription from these promoters. In the present study MEL1 and lacZ were used to construct a vector capable of measuring the divergent expression initiated by the MAL6T-MAL6S bi-directional promoter. Our observations demonstrate that the expression of both reporter genes was regulated in a similar fashion to the native MAL6T and MAL6S genes, and that induction was dependent upon the presence of a functional MALR activator gene. The results confirmed that the MAL6T-MAL6S promoter was co-ordinately regulated, repressed by glucose, induced by maltose, and that basal expression was more active in the MAL6S direction than in the MAL6T direction.
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Registered trials
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