ArticleCalcified tissue international1995
Bone mineral density in feline mucopolysaccharidosis VI measured using dual-energy X-ray absorptiometry.
Article in Calcified tissue international, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- Relationship between Feline Knee Joint Osteoarthritis and Bone Mineral Density Quantified Using Computed Tomography and Computed Digital Absorptiometry.Animals : an open access journal from MDPI · 2024Article
- Selection of X-ray Tube Settings for Relative Bone Density Quantification in the Knee Joint of Cats Using Computed Digital Absorptiometry.Sensors (Basel, Switzerland) · 2024Article
- Evaluation of bone health in patients with mucopolysaccharidosis.Journal of bone and mineral metabolism · 2022Article
- Molecular genetics and metabolism, special edition: Diagnosis, diagnosis and prognosis of Mucopolysaccharidosis IVA.Molecular genetics and metabolism · 2018Review
- Pathogenesis and treatment of spine disease in the mucopolysaccharidoses.Molecular genetics and metabolism · 2016Review
- Obstructive airway in Morquio A syndrome, the past, the present and the future.Molecular genetics and metabolism · 2016Article
- Morphometric description of the feline radius and ulna generated from computed tomography.Journal of feline medicine and surgery · 2015Article
- Assessment of bone mineral density by dual energy x-ray absorptiometry in patients with mucopolysaccharidoses.Orphanet journal of rare diseases · 2013Article
- Animal models for mucopolysaccharidosis disorders and their clinical relevance.Acta paediatrica (Oslo, Norway : 1992) · 2007Review
- Early-onset osteoporosis with high bone turnover in children with Morquio-Brailsford syndrome.Rheumatology international · 2006Article
- Enzyme replacement therapy from birth in a feline model of mucopolysaccharidosis type VI.The Journal of clinical investigation · 1997Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Dual-energy X-ray absorptiometry (DXA) was used to determine the in vivo bone mineral density (BMD) and bone mineral content (BMC) of lumbar vertebrae in six cats affected with the inherited lysosomal storage disease mucopolysaccharidosis VI (MPS VI). DXA was also performed on MPS cats that had a bone marrow transplant (BMT) and total body irradiation (TBI) (MPS + BMT; n = 7), normal cats that had a bone marrow transplant, and TBI (control + BMT; n = 8) and normal cats (control; n = 14). Following euthanasia, one of the lumbar vertebrae that had been scanned (L5) was harvested and bone volume (BV/TV%) was determined by histomorphometry. The in vivo BMD and BMD measurements were compared with the BV/TV%. There was a greater BMD and BMC in the MPS + BMT cats compared with the MPS cats but the difference was not statistically significant. However, there was a greater BV/TV% in the MPS + BMT cats compared with the MPS cats and the difference was significant (P = 0.0152). Correlation between the noninvasive in vivo DXA measurements of BMD and BMC and the BV/TV% was significant (r2 = 0.767, P < 0.0001; r2 = 0.504, P < 0.0001). Noninvasive in vivo DXA was a rapid and precise method for measuring the lumbar BMD and BMC in cats and it correlated well with histomorphometric determination of bone mass. Further, the response of inherited storage diseases such as MPS VI to therapy, such as BMT, could be monitored in a longitudinal fashion using DXA.
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Registered trials
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