ArticleJournal of clinical microbiology1995
Phenotypic and genotypic analysis of variability in Aspergillus fumigatus.
Article in Journal of clinical microbiology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
22 citing papers in PubMed, 72 citations in OpenAlex.
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- Article
- A review molecular typing methods for Aspergillus flavus isolates.Mycopathologia · 2011Review
- Phenotypic characteristics of isolates of Aspergillus section Fumigati from different geographic origins and their relationships with genotypic characteristics.BMC infectious diseases · 2011Article
- Re-identification of Aspergillus fumigatus sensu lato based on a new concept of species delimitation.Journal of microbiology (Seoul, Korea) · 2010Article
- Identification of Paecilomyces variotii in clinical samples and settings.Journal of clinical microbiology · 2010Article
- Molecular studies reveal frequent misidentification of Aspergillus fumigatus by morphotyping.Eukaryotic cell · 2006Article
- Mistaken identity: Neosartorya pseudofischeri and its anamorph masquerading as Aspergillus fumigatus.Journal of clinical microbiology · 2005Article
- Aspergillus fumigatus variant with decreased susceptibility to multiple antifungals.Antimicrobial agents and chemotherapy · 2004Article
- Evaluation of performance of four genotypic methods for studying the genetic epidemiology of Aspergillus fumigatus isolates.Journal of clinical microbiology · 2002Article
- Genetic polymorphism of Aspergillus fumigatus in clinical samples from patients with invasive aspergillosis: investigation using multiple typing methods.Journal of clinical microbiology · 2001Article
- Genetic variability within the Aspergillus viridinutans species.Folia microbiologica · 2000Article
- Aspergillus fumigatus and aspergillosis.Clinical microbiology reviews · 1999Review
- Phylogenetic relationships of varieties and geographical groups of the human pathogenic fungus Histoplasma capsulatum Darling.Journal of clinical microbiology · 1999Article
- The evolutionary biology and population genetics underlying fungal strain typing.Clinical microbiology reviews · 1999Review
- Microsatellite markers for typing Aspergillus fumigatus isolates.Journal of clinical microbiology · 1998Article
- Molecular epidemiological study of Aspergillus fumigatus in a bone marrow transplantation unit by PCR amplification of ribosomal intergenic spacer sequences.Journal of clinical microbiology · 1998Article
- Genetic diversity among clinical and environmental isolates of Aspergillus fumigatus.Infection and immunity · 1997Article
- Ochratoxin production by Aspergillus species.Applied and environmental microbiology · 1996Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sixty-one isolates and collection strains of Aspergillus fumigatus were compared for their phenotypic (morphological features and isoenzyme profiles) and genotypic (restriction enzyme-generated mitochondrial DNA and ribosomal DNA profiles and random amplified polymorphic DNA patterns) features. The examined strains exhibited highly variable colony morphologies and growth rates at different temperatures, but their micromorphologies and conidial diameters were characteristic of the species. Of the isoenzymes studied, the beta-arylesterase and phosphatase patterns were the most divergent, and the 61 strains could be classified into seven groups. The glucose 6-phosphate dehydrogenase and catalase isoenzyme patterns displayed only a limited variability, while the profiles of superoxide dismutase, lactate dehydrogenase, and glutamate dehydrogenase were highly conserved. The HaeIII-generated mitochondrial DNA patterns and SmaI-digested repetitive DNA and ribosomal DNA hybridization patterns of almost all strains were also invariable. The level of variation was much higher when random amplified polymorphic DNA analysis was applied. Although the patterns of the strains were very similar with most of the primers, the application of some primers made it possible to cluster the A. fumigatus isolates into several groups. The results indicate that the random amplified polymorphic DNA technique could be used more efficiently than isoenzyme analysis for typing A. fumigatus isolates. A good correlation was found between the dendrograms obtained from the isoenzyme and random amplified polymorphic DNA data, but the isoenzyme and amplified DNA patterns did not correlate with the pathogenicity, pigment production, or geographical origin of the strains. One "A. fumigatus" strain (strain FRR 1266) exhibited unique isoenzyme, mitochondrial DNA, ribosomal DNA, and random amplified polymorphic DNA patterns; it is proposed that this strain represents a new species of the section Fumigati.
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