ArticleNucleic acids research1995
A novel PRD I and TG binding activity involved in virus-induced transcription of IFN-A genes.
Article in Nucleic acids research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 35 citations in OpenAlex.
- Critical role of interferon-α constitutively produced in human hepatocytes in response to RNA virus infection.PloS one · 2014Article
- Impairment of interferon-induced IRF-7 gene expression due to inhibition of ISGF3 formation by trichostatin A.Journal of virology · 2003Article
- Repression by homeoprotein pitx1 of virus-induced interferon a promoters is mediated by physical interaction and trans repression of IRF3 and IRF7.Molecular and cellular biology · 2002Article
- Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection.Journal of virology · 2002Article
- Repression of virus-induced interferon A promoters by homeodomain transcription factor Ptx1.Molecular and cellular biology · 2000Article
- Structural and functional analysis of interferon regulatory factor 3: localization of the transactivation and autoinhibitory domains.Molecular and cellular biology · 1999Article
- Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7.The EMBO journal · 1998Article
- Primary activation of interferon A and interferon B gene transcription by interferon regulatory factor 3.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation.Molecular and cellular biology · 1998Article
- Constitutive activation of Epstein-Barr virus (EBV) nuclear antigen 1 gene transcription by IRF1 and IRF2 during restricted EBV latency.Molecular and cellular biology · 1997Article
- The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.Molecular and cellular biology · 1996Article
- Identification of distal silencing elements in the murine interferon-A11 gene promoter.The Biochemical journal · 1996Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Comparative analysis of the inducible elements of the mouse interferon A4 and A11 gene promoters (IE-A4 and IE-A11) by transient transfection experiments, DNase 1 footprinting and electrophoretic mobility shift assays resulted in identification of a virus-induced binding activity suggested to be involved in NDV-induced activation of transcription of these genes. The virus-induced factor, termed VIF, is activated early by contact of virions with cells. It specifically recognizes the PRD I-like domain shared by both inducible elements, as well as the TG-like domain of IE-A4. This factor, distinct from the IRF-1, IRF-2 and the alpha F1 binding proteins and presenting a different affinity pattern from that of the TG protein, is proposed as a candidate for IFN-type I gene regulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.