Evidence map›Paper›PMID 8554510›Full record

ArticleThe Biochemical journal1995

Identification of polymorphism at the glutathione S-transferase, GSTM3 locus: evidence for linkage with GSTM1*A.

A Inskip, J Elexperu-Camiruaga, N Buxton, P S Dias, J MacIntosh, D Campbell, P W Jones, L Yengi, J A Talbot, R C Strange

Open access · bronzeAbstract read
In one paragraph

Article in The Biochemical journal, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 3 syntheses or guidelines pooled it, 181 citations in OpenAlex.

  1. Pooled it
  2. Phase I and II enzyme polymorphisms as risk factors for Barrett's esophagus and esophageal adenocarcinoma: a systematic review and meta-analysis.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2009
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  7. Frontiers in molecular biosciences · 2021
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  14. Childhood brain tumors and maternal cured meat consumption in pregnancy: differential effect by glutathione S-transferases.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2011
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

A InskipDepartment of Neurosurgery, North Staffordshire Hospital, Stoke-on-Trent, Staffordshire, U.K.
J Elexperu-Camiruaga
N Buxton
P S Dias
J MacIntosh
D Campbell
P W Jones
L Yengi
J A Talbot
R C Strange
Keele University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allelism in the glutathione S-transferase, GSTM3 gene has been identified using PCR with specific primers to exon 6/exon 7. Sequencing showed the mutant GSTM3*B allele to have a three-base deletion in intron 6 with a frequency of 0.158. The mutation generates a recognition sequence, 5'-AAGATA-3', for the negative transcription factor YY1. GSTM3*B was significantly associated with GSTM1*A.

Indexed as

Genetic LinkagePolymorphism, GeneticPolymorphism, Restriction Fragment LengthBase SequenceBinding SitesDNA-Binding ProteinsErythroid-Specific DNA-Binding FactorsExonsGene DeletionGene FrequencyGlutathione TransferaseHumansIntronsMolecular Sequence DataNeoplasmsTranscription FactorsDNA-Binding ProteinsErythroid-Specific DNA-Binding FactorsGlutathione TransferaseTranscription FactorsYY1 protein, humanYY1 Transcription Factor

Identifiers

PMID8554510
PMCPMC1136172
OpenAlexW2340994381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.