Multiple mutations in a specific gene in a small geographic area: a common phenomenon?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

8 citing papers in PubMed.

1. Clan genomics: From OMIM phenotypic traits to genes and biology.American journal of medical genetics. Part A · 2021
   Article
2. Epidemiological and Molecular Characterization of a Mexican Population Isolate with High Prevalence of Limb-Girdle Muscular Dystrophy Type 2A Due to a Novel Calpain-3 Mutation.PloS one · 2017
   Article
3. Previously reported new type of autosomal recessive primary microcephaly is caused by compound heterozygous ASPM gene mutations.Cell cycle (Georgetown, Tex.) · 2014
   Article
4. A single nucleotide substitution that abolishes the initiator methionine codon of the GLDC gene is prevalent among patients with glycine encephalopathy in Jerusalem.Journal of human genetics · 2005
   Article
5. Structure of the SLC7A7 gene and mutational analysis of patients affected by lysinuric protein intolerance.American journal of human genetics · 2000
   Article
6. DNA studies of limb-girdle muscular dystrophy type 2A in the Amish exclude a modifying mitochondrial gene and show no evidence for a modifying nuclear gene.American journal of human genetics · 1997
   Article
7. The Réunion paradox and the digenic model.American journal of human genetics · 1996
   Article
8. Glutaric aciduria type I in the Arab and Jewish communities in Israel.American journal of human genetics · 1996
   Article

Corrections and comments

• Commented on by
  The Réunion paradox and the digenic model.1996
• Comment on
  Preferential localization of the limb-girdle muscular dystrophy type 2A gene in the proximal part of a 1-cM 15q15.1-q15.3 interval.1995

Authors and funding

3 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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