Evidence map›Paper›PMID 8552598›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America1996

Structural variation of the pseudoautosomal region between and within inbred mouse strains.

D Kipling, H E Wilson, E J Thomson, M Lee, J Perry, S Palmer, A Ashworth, H J Cooke

Open access · greenAbstract readComparative Study
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  9. A pronounced evolutionary shift of the pseudoautosomal region boundary in house mice.Mammalian genome : official journal of the International Mammalian Genome Society · 2012
    Article
  10. Article
  11. Dissecting the mammalian synaptonemal complex using targeted mutations.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2007
    Review
  12. Meiotic instability of chicken ultra-long telomeres and mapping of a 2.8 megabase array to the W-sex chromosome.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2005
    Article
  13. Article
  14. Article
  15. Article
  16. A gene spans the pseudoautosomal boundary in mice.Proceedings of the National Academy of Sciences of the United States of America · 1997
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

D KiplingMedical Research Council Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom.
H E Wilson
E J Thomson
M Lee
J Perry
S Palmer
A Ashworth
H J Cooke
Medical Research Council · GBMRC Human Genetics UnitWestern General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pseudoautosomal region (PAR) is a segment of shared homology between the sex chromosomes. Here we report additional probes for this region of the mouse genome. Genetic and fluorescence in situ hybridization analyses indicate that one probe, PAR-4, hybridizes to the pseudoautosomal telomere and a minor locus at the telomere of chromosome 9 and that a PCR assay based on the PAR-4 sequence amplifies only the pseudoautosomal locus (DXYHgu1). The region detected by PAR-4 is structurally unstable; it shows polymorphism both between mouse strains and between animals of the same inbred strain, which implies an unusually high mutation rate. Variation occurs in the region adjacent to a (TTAGGG)n array. Two pseudoautosomal probes can also hybridize to the distal telomeres of chromosomes 9 and 13, and all three telomeres contain DXYMov15. The similarity between these telomeres may reflect ancestral telomere-telomere exchange.

Indexed as

TelomereX ChromosomeY ChromosomeAnimalsBase SequenceChromosome MappingChromosomes, Artificial, YeastCloning, MolecularDNA PrimersMiceMice, Inbred StrainsMolecular Sequence DataPolymorphism, Restriction Fragment LengthDNA Primers

Identifiers

PMID8552598
PMCPMC40200
OpenAlexW2075183870

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.