ArticleJournal of bacteriology1996
Conserved cis-acting promoter elements are required for density-dependent transcription of Agrobacterium tumefaciens conjugal transfer genes.
Article in Journal of bacteriology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers.
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Who cites it
102 citing papers in PubMed, 271 citations in OpenAlex.
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- Inhibiting Biofilm Formation via Simultaneous Application of Nitric Oxide and Quorum Quenching Bacteria.Membranes · 2023Article
- Agrobacterium tumefaciens: a Transformative Agent for Fundamental Insights into Host-Microbe Interactions, Genome Biology, Chemical Signaling, and Cell Biology.Journal of bacteriology · 2023Review
- Diversity of Bacteria with Quorum Sensing and Quenching Activities from Hydrothermal Vents in the Okinawa Trough.Microorganisms · 2023Article
- Involvement of a Quorum Sensing Signal Molecule in the Extracellular Amylase Activity of the ThermophilicMicroorganisms · 2021Article
- Quorum Sensing Inhibitors: Curbing Pathogenic Infections through Inhibition of Bacterial Communication.Iranian journal of pharmaceutical research : IJPR · 2021Review
- Co-dependent and Interdigitated: Dual Quorum Sensing Systems Regulate Conjugative Transfer of the Ti Plasmid and the At Megaplasmid inFrontiers in microbiology · 2020Article
- Destabilization of the Tumor-Inducing Plasmid from an Octopine-TypeG3 (Bethesda, Md.) · 2019Article
- Identification of Quorum-Sensing Molecules ofMolecules (Basel, Switzerland) · 2019Article
- Characterization and Transcriptome Studies of Autoinducer Synthase Gene from Multidrug ResistantGenes · 2019Article
- Quorum-dependent transfer of the opine-catabolic plasmid pAoF64/95 is regulated by a novel mechanism involving inhibition of the TraR antiactivator TraM.MicrobiologyOpen · 2019Article
- Biofilm inhibition and pathogenicity attenuation in bacteria byRoyal Society open science · 2018Article
- Ecological and evolutionary dynamics of a model facultative pathogen: Agrobacterium and crown gall disease of plants.Environmental microbiology · 2018Review
- Quorum Sensing and Spoilage Potential of Psychrotrophic Enterobacteriaceae Isolated from Milk.BioMed research international · 2018Article
- Isolation and Characterization of N-acyl Homoserine Lactone-Producing Bacteria From Cattle Rumen and Swine Intestines.Frontiers in cellular and infection microbiology · 2018Article
- Host modification of a bacterial quorum-sensing signal induces a phenotypic switch in bacterial symbionts.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Quorum Sensing Communication Modules for Microbial Consortia.ACS synthetic biology · 2016Article
42 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Ti plasmids of Agrobacterium tumefaciens, in addition to transferring oncogenic DNA to the nuclei of infected plant cells, can conjugally transfer between agrobacteria. Conjugation of wide-host-range octopine-type Ti plasmids requires a tumor-released arginine derivative called octopine. Octopine stimulates expression of the traR gene, whose product directly activates other tra genes in the presence of an acylated homoserine lactone called Agrobacterium autoinducer (AAI). We have localized the transcription starts of three tra promoters and find conserved elements (tra boxes) at virtually identical positions upstream of each promoter. Disruption of these tra boxes abolished induction of each promoter. Deletion analysis of the traI promoter indicates that tra boxes are the only upstream elements required for transcriptional activation. Since Ti plasmid donor cells both produce and respond to AAI, we tested whether expression of tra promoters was enhanced by high concentrations of bacteria. Both tra gene expression and conjugation itself were strongly stimulated either by high donor densities or by exogenous AAI.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.