Evidence map›Paper›PMID 8550447›Full record

ArticleJournal of bacteriology1996

Comparative genome mapping of Pseudomonas aeruginosa PAO with P. aeruginosa C, which belongs to a major clone in cystic fibrosis patients and aquatic habitats.

K D Schmidt, B Tümmler, U Römling

Abstract readComparative Study
In one paragraph

Article in Journal of bacteriology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed.

  1. Article
  2. Molecular Mechanisms Underlying the Pathogenicity ofMedicina (Kaunas, Lithuania) · 2026
    Review
  3. Review
  4. Article
  5. Community-acquiredFrontiers in pediatrics · 2025
    Article
  6. Inhibition ofAntimicrobial agents and chemotherapy · 2024
    Article
  7. Infectious medicine · 2023
    Review
  8. More than just a gel: the extracellular matrixome ofFrontiers in molecular biosciences · 2023
    Article
  9. Structural genome variants ofFrontiers in microbiology · 2023
    Article
  10. Article
  11. Article
  12. PreventingACS applied bio materials · 2021
    Article
  13. Article
  14. International journal of molecular sciences · 2021
    Review
  15. Review
  16. Article
  17. Metabolomic studies of Pseudomonas aeruginosa.World journal of microbiology & biotechnology · 2019
    Review
  18. Article
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

K D SchmidtKlinische Forschergruppe, Institut für Biophysikalische Chemie und Pädiatrische Pneumologie, Medizinische Hochschule Hannover, Germany.
B Tümmler
U Römling

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A physical and genetic map was constructed for Pseudomonas aeruginosa C. Mainly, two-dimensional methods were used to place 47 SpeI, 8 PacI, 5 SwaI, and 4 I-CeuI sites onto the 6.5-Mb circular chromosome. A total of 21 genes, including the rrn operons and the origin of replication, were located on the physical map. Comparison of the physical and genetic map of strain C with that of the almost 600-kb-smaller genome of P. aeruginosa reference strain PAO revealed conservation of gene order between the two strains. A large-scale mosaic structure which was due to insertions of blocks of new genetic elements which had sizes of 23 to 155 kb and contained new SpeI sites was detected in the strain C chromosome. Most of these insertions were concentrated in three locations: two are congruent with the ends of the region rich in biosynthetic genes, and the third is located in the proposed region of the replication terminus. In addition, three insertions were scattered in the region rich in biosynthetic genes. The arrangement of the rrn operons around the origin of replication was conserved in C, PAO, and nine other examined independent strains.

Indexed as

Genome, BacterialChromosome MappingCystic FibrosisDeoxyribonucleases, Type II Site-SpecificDNA ProbesElectrophoresis, Gel, Pulsed-FieldElectrophoresis, Gel, Two-DimensionalHumansOperonPseudomonas aeruginosaWater MicrobiologyDeoxyribonucleases, Type II Site-SpecificDNA Probes

Identifiers

PMID8550447
PMCPMC177624

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.