ReviewDrugs1995
Fluoroquinolone toxicities. An update.
Review in Drugs, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 88 citations in OpenAlex.
- Randomised double-blind comparison of oral gatifloxacin and co-amoxiclav for acute exacerbation of chronic Bronchitis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2003Trial
- Clinafloxacin pharmacokinetics in subjects with various degrees of renal function.Antimicrobial agents and chemotherapy · 2001Trial
- Early postoperative fluoroquinolone use is associated with an increased revision rate after arthroscopic rotator cuff repair.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2017Article
- Antibiotic Prescriptions and Prophylaxis in Italian Children. Is It Time to Change? Data from the ARPEC Project.PloS one · 2016Article
- Systemic use of fluoroquinolone in children.Korean journal of pediatrics · 2013Article
- Oxidative stress induced by fluoroquinolones on treatment for complicated urinary tract infections in Indian patients.Journal of young pharmacists : JYP · 2011Article
- Evidence of tendinitis provoked by fluoroquinolone treatment: a case-control study.Drug safety · 2006Article
- Safety of fluoroquinolones: An update.The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses · 2002Article
- Fluoroquinolone-induced renal failure.Drug safety · 2000Review
- Cutaneous reactions to drugs. An analysis of spontaneous reports in four Italian regions.British journal of clinical pharmacology · 1999Article
- Comparative tolerability of the newer fluoroquinolone antibacterials.Drug safety · 1999Review
- Quinolones: which generation for which microbe?The Western journal of medicine · 1999Review
- The new fluoroquinolones: A critical review.The Canadian journal of infectious diseases = Journal canadien des maladies infectieuses · 1999Article
- Quinolones in the aged.Drugs · 1999Review
- Severe Acute Axonal Neuropathy Induced by Ciprofloxacin: A Case Report.Case reports in neurologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The main types of adverse effects associated with quinolones are uncommon and reversible and vary in frequency among different agents. Phototoxicity appears more frequent with lomefloxacin than with some other quinolones. Three mechanisms have been proposed to explain the neurotoxic effects, including rare proconvulsant activity, associated with quinolone therapy. Arthropathy remains a dilemma for paediatricians deciding whether to use quinolones in growing children. Importantly, the experience with temafloxacin, which has now been withdrawn from the market, emphasises the need for thorough postmarketing surveillance. Nonetheless, it should be remembered that the fluoroquinolones as a group are effective and very well tolerated antimicrobial drugs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.