Evidence map›Paper›PMID 8547161›Full record

ArticleInternational journal of legal medicine1995

Validation of mitochondrial DNA sequencing for forensic casework analysis.

M R Wilson, J A DiZinno, D Polanskey, J Replogle, B Budowle

Abstract read
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In one paragraph

Article in International journal of legal medicine, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 349 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
  5. Review
  6. DNA and protein analyses of hair in forensic genetics.International journal of legal medicine · 2023
    Review
  7. Article
  8. Mitochondrial DNA Analysis.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Rapidly mutating Y-STR analyses of compromised forensic samples.International journal of legal medicine · 2018
    Article
  17. Article
  18. Forensic Human Identification Using Skin Microbiomes.Applied and environmental microbiology · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

M R WilsonForensic Science Research and Training Center, FBI Academy, Quantico, VA 22135, USA.
J A DiZinno
D Polanskey
J Replogle
B Budowle
Federal Bureau of Investigation · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two sets of studies were performed to evaluate the forensic utility of sequencing human mitochondrial DNA (mtDNA) derived from various tissues and amplified by the polymerase chain reaction (PCR). Sequencing was performed on a Perkin-Elmer/Applied Biosystems Division (PE/ABD) automated DNA sequencer (model 373A). The first set of experiments included typical validation studies that had previously been conducted on forensic DNA markers, such as: chemical contaminant effects on DNA from blood and semen and the effect of typing DNA extracted from body fluid samples deposited on various substrates. A second set of experiments was performed strictly on human hair shafts. These studies included typing mtDNA from hairs that were: (1) from different body areas, (2) chemically treated, (3) from deceased individuals, and (4) deliberately contaminated with various body fluids. The data confirm that PCR-based mtDNA typing by direct automated sequencing is a valid and reliable means of forensic identification.

Indexed as

Polymerase Chain ReactionAnimalsBase SequenceBlood StainsDNA FingerprintingDNA, MitochondrialHairHumansImmunoglobulin Variable RegionMolecular Sequence DataReproducibility of ResultsSemenSequence Analysis, DNASpecimen HandlingDNA, MitochondrialImmunoglobulin Variable Region

Identifiers

PMID8547161
OpenAlexW2049925645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.