Evidence map›Paper›PMID 8546334›Full record

ArticleAnatomy and embryology1995

Potential intraembryonic hemogenic sites at pre-liver stages in the mouse.

J A Garcia-Porrero, I E Godin, F Dieterlen-Lièvre

Abstract read
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Article in Anatomy and embryology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Article
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  11. RUNX1 and the endothelial origin of blood.Experimental hematology · 2018
    Review
  12. Article
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  14. Review
  15. Article
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  18. Review
  19. A view of human haematopoietic development from the Petri dish.Nature reviews. Molecular cell biology · 2017
    Review
  20. Insights into blood cell formation from hemogenic endothelium in lesser-known anatomic sites.Developmental dynamics : an official publication of the American Association of Anatomists · 2016
    Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

J A Garcia-PorreroDepartamento de Anatomia y Biologia Cellular, Facultad de Medicina, Universidad de Cantabria, Santander, Spain.
I E Godin
F Dieterlen-Lièvre

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the course of a previous experimental study on the early development of the mouse embryo hemopoietic system, we found that, at the 10-25 pairs of somite stages, the para-aortic splanchnopleure contains hemopoietic progenitors. Trying to discover a structural basis for this potentiality, we have looked for cytological signs of hemopoiesis in the embryo proper between 8.5 and 12 days post-coitum, i.e. prior to full-blown fetal liver hemopoiesis. Two suggestive findings are reported: (1) intra-arterial hemopoietic cells aggregates are present in the omphalomesenteric and umbilical arteries and to a lesser degree in the dorsal aorta; (2) cells groups resembling yolk sac blood islands are observed in the mesentery. The intra-arterial aggregates are strikingly similar to the intra-aortic clusters of avian embryos. These cytological aspects provide the anatomical basis underlying recent functional data that revealed the hemogenic capacity of the para-aortic splanchnopleure.

Indexed as

Embryonic and Fetal DevelopmentHematopoiesisAnimalsArteriesBlood VesselsEmbryo, MammalianLiverMesenteryMiceMice, Inbred BALB CSplanchnic Circulation

Identifiers

PMID8546334

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.