Characterization of the expressed CIITA allele in the class II MHC transcriptional mutant RJ2.2.5.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

15 citing papers in PubMed.

1. Selective control of HLA-DRB1 and HLA-DQA1 transcription through DR/DQ super enhancer microelements.Cell reports · 2026
   Article
2. The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins.International journal of molecular sciences · 2021
   Review
3. Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III.PloS one · 2016
   Article
4. Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment.Nucleic acids research · 2015
   Article
5. PU.1 binds to a distal regulatory element that is necessary for B cell-specific expression of CIITA.Journal of immunology (Baltimore, Md. : 1950) · 2010
   Article
6. CIITA or RFX coding region loss of function mutations occur rarely in diffuse large B-cell lymphoma cases and cell lines with low levels of major histocompatibility complex class II expression.Haematologica · 2009
   Article
7. The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions.The Journal of experimental medicine · 2008
   Article
8. Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A.Nucleic acids research · 2006
   Article
9. Defective class II transactivator expression in a B lymphoma cell line.Leukemia · 2004
   Article
10. The bare lymphocyte syndrome: molecular clues to the transcriptional regulation of major histocompatibility complex class II genes.American journal of human genetics · 1999
    Review
11. The MHC class II transactivator (CIITA) requires conserved leucine charged domains for interactions with the conserved W box promoter element.Nucleic acids research · 1998
    Article
12. CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo.Proceedings of the National Academy of Sciences of the United States of America · 1998
    Article
13. Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway.The Journal of experimental medicine · 1998
    Article
14. Efficient repression of endogenous major histocompatibility complex class II expression through dominant negative CIITA mutants isolated by a functional selection strategy.Molecular and cellular biology · 1997
    Article
15. An isotype-specific activator of major histocompatibility complex (MHC) class II genes that is independent of class II transactivator.The Journal of experimental medicine · 1997
    Article

Corrections and comments

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Authors and funding

4 authors.

Funding

Abstract

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