Evidence map›Paper›PMID 8536963›Full record

ArticleGenetics1995

Integrated maps of the chromosomes in Dictyostelium discoideum.

W F Loomis, D Welker, J Hughes, D Maghakian, A Kuspa

Abstract read
In one paragraph

Article in Genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Targeted gene insertion for molecular medicine.Journal of molecular medicine (Berlin, Germany) · 2008
    Review
  4. Article
  5. Article
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  7. Article
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  9. Article
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  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Ordered yeast artificial chromosome clones representing the Dictyostelium discoideum genome.Proceedings of the National Academy of Sciences of the United States of America · 1996
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

W F LoomisDepartment of Biology, University of California at San Diego, La Jolla 92093, USA.
D Welker
J Hughes
D Maghakian
A Kuspa
University of California San Diego · US

Funding

ROLE OF MDR-RELATED GENES IN DICTYOSTELIUM DEVELOPMENTR01GM052359 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI KUSPA, ADAM · 1995 to 2008
$2.1M
NHGRI NIH HHS HG-00096NIGMS NIH HHS R01 GM052359
6 · The paper itself

Abstract

Detailed maps of the six chromosomes that carry the genes of Dictyostelium discoideum were constructed by correlating physically mapped regions with parasexually determined linkage groups. Chromosomally assigned regions were ordered and positioned by the pattern of altered fragment sizes seen in a set of restriction enzyme mediated integration-restriction fragment length polymorphism (REMI-RFLP) strains each harboring an inserted plasmid that carries sites recognized by NotI, SstI, SmaI, BglI and ApaI. These restriction enzymes were used to digest high molecular weight DNA prepared from more than 100 REMI-RFLP strains and the resulting fragments were separated and sized by pulsed-field gels. More than 150 gene probes were hybridized to blots of these gels and used to map the insertion sites relative to flanking restriction sites. In this way, we have been able to restriction map the 35 mb genome as well as determine the map position of more than 150 genes to with approximately 40 kb resolution. These maps provide a framework for subsequent refinement.

Indexed as

Chromosomes, FungalAnimalsChromosome MappingCloning, MolecularDictyosteliumGenes, FungalPolymorphism, Restriction Fragment Length

Identifiers

PMID8536963
PMCPMC1206713
OpenAlexW2131853830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.