Evidence map›Paper›PMID 8536799›Full record

ReviewExperientia1995

Analysis of gene function in Dictyostelium.

A Kuspa, T Dingermann, W Nellen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Experientia, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 2 countries.

A KuspaDepartment of Biochemistry, Baylor College of Medicine, Houston, Texas 77030, USA.
T Dingermann
W Nellen
Baylor College of Medicine · USGoethe University Frankfurt · DEMax Planck Institute of Biochemistry · DE

Funding

ROLE OF MDR-RELATED GENES IN DICTYOSTELIUM DEVELOPMENTR01GM052359 · NIGMS · BAYLOR COLLEGE OF MEDICINE · PI KUSPA, ADAM · 1995 to 2008
$2.1M
NIGMS NIH HHS R01 GM052359
6 · The paper itself

Abstract

Over the past ten years, powerful molecular genetic techniques have been developed to analyze gene function in Dictyostelium. DNA-mediated transformation using a variety of selections and vectors has allowed the introduction of wild-type or modified genes that are under various forms of transcriptional control. Homologous recombination is efficient and can be used to modify the genome in precise ways. In addition, it is now possible to clone genes based on their mutant phenotype alone, either by insertional mutagenesis, or by screening antisense expression cDNA libraries. Finally, a nearly complete physical map of the genome is available and so genes are easily mapped by physical techniques. We discuss many of these advances within the context of major research problems presently under study.

Indexed as

AnimalsChromosome MappingDictyosteliumGene ExpressionGene TargetingMutagenesis, InsertionalProtein EngineeringRNA, AntisenseRNA, Antisense

Identifiers

PMID8536799
OpenAlexW1977986148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.