ArticleArchives of disease in childhood. Fetal and neonatal edition1995
Use of specific immunoradiometric assay to determine preterm neonatal insulin-glucose relations.
Article in Archives of disease in childhood. Fetal and neonatal edition, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 25 citations in OpenAlex.
- Article
- Management strategies for neonatal hypoglycemia.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2013Review
- Hyperinsulinaemic hypoglycaemia in preterm neonates.Archives of disease in childhood. Fetal and neonatal edition · 2004Article
- Neonatal hypoglycaemia in Nepal 2. Availability of alternative fuels.Archives of disease in childhood. Fetal and neonatal edition · 2000Article
- Third trimester fetal growth and measures of carbohydrate and lipid metabolism in umbilical venous blood at term.Archives of disease in childhood. Fetal and neonatal edition · 1997Article
- Hypoglycaemia of the newborn: a review.Bulletin of the World Health Organization · 1997Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Highly specific immunoradiometric assays were used to measure plasma concentrations of insulin, proinsulin, and 32-33 split proinsulin in neonates (n = 16). Neonatal plasma insulin concentrations were high relative to blood glucose concentrations and compared with adult insulin-glucose relations. Concentrations of proinsulin and 32-33 split proinsulin together accounted for 34-70% of the total concentration of insulin and pro-peptides. This study confirms the need to use a specific assay and neonatal reference data in the diagnosis of neonatal hyperinsulinism, and shows that neonatal pancreatic beta cell function may differ from that of older subjects.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.