ArticleNucleic acids research1995
Intronic U14 snoRNAs of Xenopus laevis are located in two different parent genes and can be processed from their introns during early oogenesis.
Article in Nucleic acids research, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 25 citations in OpenAlex.
- Differential accumulation of U14 snoRNA and hsc70 mRNA in Chinese hamster cells after exposure to various stress conditions.Cell stress & chaperones · 2002Article
- The ribosomal RNA processing machinery is recruited to the nucleolar domain before RNA polymerase I during Xenopus laevis development.The Journal of cell biology · 2000Article
- The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization.The EMBO journal · 1998Article
- Conserved boxes C and D are essential nucleolar localization elements of U14 and U8 snoRNAs.The EMBO journal · 1998Article
- The U14 snoRNA is required for 2'-O-methylation of the pre-18S rRNA in Xenopus oocytes.RNA (New York, N.Y.) · 1998Article
- The sequence of the 5' end of the U8 small nucleolar RNA is critical for 5.8S and 28S rRNA maturation.Molecular and cellular biology · 1997Article
- Delocalization of some small nucleolar RNPs after actinomycin D treatment to deplete early pre-rRNAs.Chromosoma · 1997Article
- Small RNA database.Nucleic acids research · 1997Article
- Identification of specific nucleotide sequences and structural elements required for intronic U14 snoRNA processing.RNA (New York, N.Y.) · 1997Article
- Elements essential for processing intronic U14 snoRNA are located at the termini of the mature snoRNA sequence and include conserved nucleotide boxes C and D.RNA (New York, N.Y.) · 1996Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
U14 is a member of the rapidly growing family of intronic small nucleolar RNAs (snoRNAs) that are involved in pre-rRNA processing and ribosome biogenesis. These snoRNA species are encoded within introns of eukaryotic protein coding genes and are synthesized via an intron processing pathway. Characterization of Xenopus laevis U14 snoRNA genes has revealed that in addition to the anticipated location of U14 within introns of the amphibian hsc70 gene (introns 4, 5 and 7), additional intronic U14 snoRNAs are also found in the ribosomal protein S13 gene (introns 3 and 4). U14 is thus far a unique intronic snoRNA in that it is encoded within two different parent genes of a single organism. Northern blot analysis revealed that U14 snoRNAs accumulate during early oocyte development and are rapidly expressed after the mid-blastula transition of developing embryos. Microinjection of hsc70 pre-mRNAs into developing oocytes demonstrated that oocytes as early as stages II and III are capable of processing U14 snoRNA from the pre-mRNA precursor. The ability of immature oocytes to process intronic snoRNAs is consistent with the observed accumulation of U14 during oocyte maturation and the developmentally regulated synthesis of rRNA during oogenesis.
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