ArticleHuman genetics1995
Refined mapping of the psoriasin gene S100A7 to chromosome 1cen-q21.
Article in Human genetics, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 17 citations in OpenAlex.
- Psoriasin promotes invasion, aggregation and survival of pancreatic cancer cells; association with disease progression.International journal of oncology · 2017Article
- Molecular and cellular impact of Psoriasin (S100A7) on the healing of human wounds.Experimental and therapeutic medicine · 2017Article
- The clinical significance of Psoriasin for non-small cell lung cancer patients and its biological impact on lung cancer cell functions.BMC cancer · 2012Article
- Expanding the psoriasis disease profile: interrogation of the skin and serum of patients with moderate-to-severe psoriasis.The Journal of investigative dermatology · 2012Article
- The expression of Psoriasin (S100A7) and CD24 is linked and related to the differentiation of mammary epithelial cells.PloS one · 2012Article
- Comprehensive evaluation of genetic variation in S100A7 suggests an association with the occurrence of allergic rhinitis.Respiratory research · 2008Article
- Jab1 is a target of EGFR signaling in ERalpha-negative breast cancer.Breast cancer research : BCR · 2008Article
- Psoriasin (S100A7) expression and invasive breast cancer.The American journal of pathology · 1999Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Psoriasin is a low molecular weight protein of the S100 family, which is highly upregulated in psoriatic epidermis, and whose function is related to skin inflammatory responses. We have applied a cDNA probe from the corresponding psoriasin gene S100A7 in a refined localisation analysis. S100A7 was mapped physically by human/rodent somatic cell hybrid analysis, and more precisely genetically by multilocus linkage analysis of 40 CEPH (Centre d'Etude du Polymorphisme Humain) families. The resulting 12-point linkage map was supported by odds of at least 1000:1, where S100A7 could be placed with a multipoint lodscore of 27.4 in an approximately 7-cM interval. The order of the 12 loci was as follows (with the best estimates of recombination frequencies given in between): AMY2B-0.091-D1S73(0.039)-D1S11(-0.053)-D1S189(-0 .017)-D1S1252 (-0.017)-D1S13(-0.078)-D1Z5(-0.051)-S100A7(-0.022)- MUC1(-0.026)-SPTA1 (-0.066)-ATP1A2(-0.014)-APOA2. Furthermore, from this map S100A7 could be assigned to the regional position of chromosome 1cen-q21. The linkage information presented should be of great value in association and linkage studies of diseases where psoriasin, or some of the several other very closely linked and functionally related genes, are seen as candidate genes, e.g. in psoriasis.
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