ArticleChromosoma1995
Immunocytology of chiasmata and chromosomal disjunction at mouse meiosis.
Article in Chromosoma, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
34 citing papers in PubMed, 83 citations in OpenAlex.
- Formation and resolution of meiotic chromosome entanglements and interlocks.Journal of cell science · 2024Review
- The pericentromeric heterochromatin of homologous chromosomes remains associated after centromere pairing dissolves in mouse spermatocyte meiosis.Chromosoma · 2019Article
- Retinoic acid-induced CYP51 nuclear translocation promotes meiosis prophase I process and is correlated to the expression of REC8 and STAG3 in mice.Biology open · 2018Article
- Article
- Meioc maintains an extended meiotic prophase I in mice.PLoS genetics · 2017Article
- Alterations in chromosomal synapses and DNA repair in apoptotic spermatocytes of Mus m. domesticus.European journal of histochemistry : EJH · 2016Article
- Article
- Suppression of the SOX2 neural effector gene by PRDM1 promotes human germ cell fate in embryonic stem cells.Stem cell reports · 2014Article
- A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice.Biology of reproduction · 2013Article
- A specific family of interspersed repeats (SINEs) facilitates meiotic synapsis in mammals.Molecular cytogenetics · 2013Article
- Interplay between synaptonemal complex, homologous recombination, and centromeres during mammalian meiosis.PLoS genetics · 2012Article
- Complex regulation of sister kinetochore orientation in meiosis-I.Journal of biosciences · 2010Review
- Analysis of meiotic prophase I in live mouse spermatocytes.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2008Article
- Meiotic pairing and segregation of achiasmate sex chromosomes in eutherian mammals: the role of SYCP3 protein.PLoS genetics · 2007Article
- Apoptosis in mouse fetal and neonatal oocytes during meiotic prophase one.BMC developmental biology · 2007Article
- Involvement of synaptonemal complex proteins in sex chromosome segregation during marsupial male meiosis.PLoS genetics · 2006Article
- The synaptonemal complex and meiotic recombination in humans: new approaches to old questions.Chromosoma · 2006Review
- Sex chromosomes, synapsis, and cohesins: a complex affair.Chromosoma · 2006Review
- Mouse SYCP2 is required for synaptonemal complex assembly and chromosomal synapsis during male meiosis.The Journal of cell biology · 2006Article
- MLH1p and MLH3p localize to precociously induced chiasmata of okadaic-acid-treated mouse spermatocytes.Genetics · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunocytological and in situ hybridization evidence supports the hypothesis that at meiosis of chiasmate organisms, chromosomal disjunction and reductional segregation of sister centromeres are integrated with synaptonemal complex functions. The Mr 125,000 synaptic protein, Syn1, present between cores of paired homologous chromosomes during pachytene of meiotic prophase, is lost from synaptonemal complexes coordinately with homolog separation at diplotene. Separation is constrained by exchanges between non-sister chromatids, the chiasmata. We show that the Mr 30,000 chromosomal core protein, Cor1, associated with sister chromatid pairs, remains an axial component of post-pachytene chromosomes until metaphase I. We demonstrate that at this time the chromatin loops are still attached to their cores. A reciprocal exchange event between two homologous non-sister chromatids is therefore immobilized by anchorage of sister chromatids to their respective cores. Cores thus contribute to the sister chromatid cohesiveness required for maintenance of chiasmata and proper chromosomal disjunction. Cor1 protein accumulates in juxtaposition to pairs of sister centromeres during metaphase I. Presumably, independent movement of sister centromeres at anaphase I is restricted by Cor1 anchorage. That reductional separation of sister centromeres is mediated by Cor1, is supported by the dissociation of Cor1 from separating sister centromeres at anaphase II and by its absence from mitotic anaphases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.