ArticleApplied and environmental microbiology1995
Orally administered bovine lactoferrin inhibits bacterial translocation in mice fed bovine milk.
Article in Applied and environmental microbiology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 60 citations in OpenAlex.
- Radioprotection of mice by lactoferrin against irradiation with sublethal X-rays.Journal of radiation research · 2014Article
- Protective effects of human lactoferrin during Aggregatibacter actinomycetemcomitans-induced bacteremia in lactoferrin-deficient mice.Antimicrobial agents and chemotherapy · 2014Article
- Isolation of a bifidogenic peptide from the pepsin hydrolysate of bovine lactoferrin.Applied and environmental microbiology · 2013Article
- Expression of lysostaphin in milk of transgenic mice affects the growth of neonates.Transgenic research · 2003Article
- Lactoferrin protects against development of hepatitis caused by sensitization of Kupffer cells by lipopolysaccharide.Clinical and diagnostic laboratory immunology · 2001Article
- Lactoferrin protects gut mucosal integrity during endotoxemia induced by lipopolysaccharide in mice.Inflammation · 2000Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Feeding of bovine milk to mice induced a high incidence of bacterial translocation from the intestines to the mesenteric lymph nodes, and the bacteria involved were mainly members of the family Enterobacteriaceae. Supplementation of the milk diet with bovine lactoferrin or a pepsin-generated hydrolysate of bovine lactoferrin resulted in significant suppression of bacterial translocation. Our findings suggest that this ability of lactoferrin to inhibit bacterial translocation may be due to its suppression of bacterial overgrowth in the guts of milk-fed mice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.