ArticleProceedings of the National Academy of Sciences of the United States of America1995
Identification of a Drosophila G protein alpha subunit (dGq alpha-3) expressed in chemosensory cells and central neurons.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 81 citations in OpenAlex.
- Heterologous investigation of metabotropic and ionotropic odorant receptors in ab3A neurons ofFrontiers in molecular biosciences · 2023Article
- Access to the odor world: olfactory receptors and their role for signal transduction in insects.Cellular and molecular life sciences : CMLS · 2018Review
- A Single Residue Mutation in the GαG3 (Bethesda, Md.) · 2018Article
- Calmodulin Enhances Cryptochrome Binding to INAD inFrontiers in molecular neuroscience · 2018Article
- Molecular Cloning and Characterization of G Alpha Proteins from the Western Tarnished Plant Bug, Lygus hesperus.Insects · 2014Article
- The stimulatory Gα(s) protein is involved in olfactory signal transduction in Drosophila.PloS one · 2011Article
- Role of G-proteins in odor-sensing and CO2-sensing neurons in Drosophila.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2010Article
- Pheromone transduction in moths.Frontiers in cellular neuroscience · 2010Article
- ROS-GC subfamily membrane guanylate cyclase-linked transduction systems: taste, pineal gland and hippocampus.Molecular and cellular biochemistry · 2010Review
- Smelling the difference: controversial ideas in insect olfaction.The Journal of experimental biology · 2009Article
- Controversy and consensus: noncanonical signaling mechanisms in the insect olfactory system.Current opinion in neurobiology · 2009Review
- Reduced odor responses from antennal neurons of G(q)alpha, phospholipase Cbeta, and rdgA mutants in Drosophila support a role for a phospholipid intermediate in insect olfactory transduction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- Odor and pheromone detection in Drosophila melanogaster.Pflugers Archiv : European journal of physiology · 2007Review
- Taste and pheromone perception in the fruit fly Drosophila melanogaster.Pflugers Archiv : European journal of physiology · 2007Review
- Galpha encoding gene family of the malaria vector mosquito Anopheles gambiae: expression analysis and immunolocalization of AGalphaq and AGalphao in female antennae.The Journal of comparative neurology · 2006Article
- Gsalpha is involved in sugar perception in Drosophila melanogaster.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2006Article
- Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo.PLoS biology · 2006Article
- G-protein gamma subunit 1 is required for sugar reception in Drosophila.The EMBO journal · 2005Article
- Altered levels of Gq activity modulate axonal pathfinding in Drosophila.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- The heterotrimeric protein Go is required for the formation of heart epithelium in Drosophila.The Journal of cell biology · 1999Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We have identified another Drosophila GTP-binding protein (G protein) alpha subunit, dGq alpha-3. Transcripts encoding dGq alpha-3 are derived from alternative splicing of the dGq alpha locus previously shown to encode two visual-system-specific transcripts [Lee, Y.-J., Dobbs, M.B., Verardi, M.L. & Hyde, D.R. (1990) Neuron 5, 889-898]. Immunolocalization studies using dGq alpha-3 isoform-specific antibodies and LacZ fusion genes show that dGq alpha-3 is expressed in chemosensory cells of the olfactory and taste structures, including a subset of olfactory and gustatory neurons, and in cells of the central nervous system, including neurons in the lamina ganglionaris. These data are consistent with a variety of roles for dGq alpha-3, including mediating a subset of olfactory and gustatory responses in Drosophila, and supports the idea that some chemosensory responses use G protein-coupled receptors and the second messenger inositol 1,4,5-trisphosphate.
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