Evidence map›Paper›PMID 8523576›Full record

ArticleJournal of virology1996

Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses.

D C Sellon, K M Walker, K E Russell, S T Perry, P Covington, F J Fuller

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 1996. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

D C SellonDepartment of Food Animal and Equine Medicine, North Carolina State University College of Veterinary Medicine, Raleigh 27606, USA.
K M Walker
K E Russell
S T Perry
P Covington
F J Fuller
North Carolina State University · US

Funding

LENTIVIRAL DISEASES--EIAV PATHOGENESISR01CA059278 · NCI · UNIVERSITY OF TEXAS ARLINGTON · PI PAYNE, SUSAN LYNNE · 1993 to 2010
$2.1M
MOLECULAR &CELLULAR BASIS OF EQUINE INFECTIOUS ANEMIAK11AI000963 · NIAID · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI SELLON, DEBRA C · 1990 to 1994
–
NCI NIH HHS CA59278NIAID NIH HHS K11-AI00963
6 · The paper itself

Abstract

Equine infectious anemia virus is a lentivirus that replicates in mature tissue macrophages of horses. Ponies were infected with equine infectious anemia virus. During febrile episodes, proviral DNA was detectable, but viral mRNA was not detectable. As cultured blood monocytes from these ponies differentiated into macrophages, viral expression was upregulated. In situ hybridization confirmed that viral transcription occurred in mature macrophages.

Indexed as

Virus ReplicationAcute DiseaseAnimalsCell DifferentiationDNA, ViralEquine Infectious AnemiaHorsesInfectious Anemia Virus, EquineMonocytesRNA, MessengerRNA, ViralUp-RegulationDNA, ViralRNA, MessengerRNA, Viral

Identifiers

PMID8523576
PMCPMC189850
OpenAlexW1878135792

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.