ReviewJournal of neuro-oncology1995
Interactions of glioma cells and extracellular matrix.
Review in Journal of neuro-oncology, 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 34 citations in OpenAlex.
- Decorin: matrix-based pan-cancer tumor suppressor.Molecular and cellular biochemistry · 2025Review
- Glycomaterials to Investigate the Functional Role of Aberrant Glycosylation in Glioblastoma.Advanced healthcare materials · 2022Review
- Survival of rats bearing advanced intracerebral F 98 tumors after glutathione depletion and microbeam radiation therapy: conclusions from a pilot project.Radiation oncology (London, England) · 2018Article
- Analysis of gene expression profiles associated with glioma progression.Molecular medicine reports · 2015Article
- Targeting ανβ3 and ανβ5 inhibits photon-induced hypermigration of malignant glioma cells.Radiation oncology (London, England) · 2011Article
- The transglutaminase 2 gene is aberrantly hypermethylated in glioma.Journal of neuro-oncology · 2011Article
- Expression of integrin alphavbeta3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature.Brain pathology (Zurich, Switzerland) · 2008Article
- The brain slice chamber, a novel variation of the Boyden Chamber Assay, allows time-dependent quantification of glioma invasion into mammalian brain in vitro.Journal of neuro-oncology · 2005Article
- Modulation of glioma cell invasion and motility by adenoviral gene transfer of PAI-1.Clinical & experimental metastasis · 2003Article
- Growth factor activity of endothelin-1 in primary astrocytes mediated by adhesion-dependent and -independent pathways.The Journal of neuroscience : the official journal of the Society for Neuroscience · 1997Article
- Assessment of laminin-mediated glioma invasion in vitro and by glioma tumors engrafted within rat spinal cord.Journal of neuro-oncology · 1996Article
- Identification of Prognostic Biomarkers for Glioblastoma Based on Transcriptome and Proteome Association Analysis.Technology in cancer research & treatmentArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The communication between tumor cells and extracellular matrix (ECM) is responsible for clinically important features of malignant gliomas, such as cerebral invasion and leptomeningeal spread. The synthesis of ECM components, ECM-degrading activities and ECM receptors as well as the interaction between ECM components and their receptors represents the molecular basis for these processes. Recent studies have shown that proteases and integrins, the major group of ECM receptors, may be over-expressed by astrocytic tumor cells. Furthermore, integrins and the hyaluronate receptor CD44 have been found to be involved in adhesion and basement membrane invasion of glioma cells. Critical issues which are poorly understood so far include the ECM composition of the normal human brain and of brain tumors, the function of individual ECM components and receptors in a neuro-oncological context, and the molecular processes mediating the diffuse invasion of glioma cells into the brain.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.