ArticleBMJ (Clinical research ed.)1995
Changes in incidence of and mortality from breast cancer in England and Wales since introduction of screening. United Kingdom Association of Cancer Registries.
Article in BMJ (Clinical research ed.), 1995. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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32 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Calcium channel blockers and risk of breast cancer: a meta-analysis of 17 observational studies.PloS one · 2014Pooled it
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- The influence of breast screening on breast cancer incidence in England: observational study based on cancer registries and bulletins of the NHS Breast Screening Programme.European journal of public health · 2024Observational
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- Mammography service screening and breast cancer mortality in New Zealand: a National Cohort Study 1999-2011.British journal of cancer · 2017Article
- Evaluation of bowel cancer registration data in England, 1996-2004.British journal of cancer · 2009Article
- A comparison of clinicopathological features and molecular markers in british and nigerian women with breast cancer.Clinical medicine. Oncology · 2008Article
- Predicted trends in long-term breast cancer survival in England and Wales.British journal of cancer · 2007Article
- A theme issue by, for, and about Africa: collaborative work between Nigeria and UK on breast cancer has been successful.BMJ (Clinical research ed.) · 2005Article
- Decreased rates of advanced breast cancer due to mammography screening in The Netherlands.British journal of cancer · 2004Article
- Geographical variation in breast cancer survival rates for women diagnosed in England between 1992 and 1994.British journal of cancer · 2004Article
- Breast cancer mortality trends in two areas of the province of Florence, Italy, where screening programmes started in the 1970s and 1990s.British journal of cancer · 2004Article
- Declining mortality from breast cancer in Yorkshire, 1983-1998: extent and causes.British journal of cancer · 2004Article
- The changing global patterns of female breast cancer incidence and mortality.Breast cancer research : BCR · 2004Review
- Effect of prenatal exposure to hydroxyprogesterone on steroidogenic enzymes in male rats.Die Naturwissenschaften · 2003Article
- Risk of breast cancer in women who attend the NHS breast screening programme: cohort study.BMJ (Clinical research ed.) · 2001Article
- How complete and accurate are cancer registrations notified by the National Health Service Central Register for England and Wales?Journal of epidemiology and community health · 2001Article
- Effect of NHS breast screening programme on mortality from breast cancer in England and Wales, 1990-8: comparison of observed with predicted mortality.BMJ (Clinical research ed.) · 2000Article
- Breast cancer screening. Screening has to be combined with good surgical and oncological services.BMJ (Clinical research ed.) · 2000Article
- Cancer trends in England and Wales. Good data and analysis are vital to improving survival.BMJ (Clinical research ed.) · 2000Article
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Abstract
objectiveTo assess the impact of the NHS breast screening programme on the incidence of and mortality from breast cancer.
designComparison of age specific incidence and mortality before and after the introduction of screening in the late 1980s.
settingEngland and Wales. SUBJECTS: Women aged over 30 years.
resultsIn 1992 the age standardised incidence of breast cancer was 40% higher than in 1979. After the introduction of screening in 1988 recorded incidence rates rose steeply in the screened age group (50-64 year olds) but not in others. In 1992 the rates levelled off at about 25% higher than in 1987. Total mortality from breast cancer has increased steadily since the 1950s; the rates increased earlier in the younger age groups. By the mid-1980s rates had begun to fall in the younger age groups; but total mortality was still among the highest in the world. Age standardised mortality in the 55-69 age group changed little during the first three years of screening but then fell steeply and in 1994 was 12% lower than in 1987.
conclusionsSince the introduction of screening there have been pronounced increases in recorded incidence in the screened age group. Cancer registries have an essential role in assessing screening programmes and cancer services. The steep decrease in mortality in 55-69 year olds which began three years after screening started is unlikely to be due to screening. The widespread adoption of treatment with tamoxifen during this period may be important. With the reduction in mortality already observed and the expected additional benefits from screening, the Health of the Nation target should be achieved.
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