Evidence map›Paper›PMID 8504255›Full record

ReviewCurrent opinion in genetics & development1993

Gene regulation: translational initiation by internal ribosome binding.

S K Oh, P Sarnow

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in genetics & development, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 42 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Programmed translational frameshifting.Microbiological reviews · 1996
    Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

S K OhDepartment of Biochemistry, Biophysics and Genetics, University of Colorado Health Sciences Center, Denver 80262.
P Sarnow
University of Colorado Health · US

Funding

STRUCTURE/FUNCTION OF THE POLIOVIRUS RNA GENOMER01AI025105 · NIAID · UNIVERSITY OF COLORADO DENVER · PI SARNOW, PETER · 1992 to 2002
$742k
VARICELLA-ZOSTER VIRUS GENE LIBRARY AND SUBUNIT VACCINEP01AG007347 · NIA · UNIVERSITY OF COLORADO DENVER · PI PIZER, LEWIS I · 1988 to 1992
–
STRUCTURE/FUNCTION OF PICORNAVIRUS RNA GENOMESR21AI025105 · NIAID · STANFORD UNIVERSITY · PI SARNOW, PETER · 1997 to 1997
–
STRUCTURE AND FUNCTION OF THE POLIOVIRUS RNA GENOMER29AI025105 · NIAID · UNIVERSITY OF COLORADO DENVER · PI SARNOW, PETER · 1987 to 1991
–
NIAID NIH HHS AI25105NIA NIH HHS AG 07347
6 · The paper itself

Abstract

During the past year, several examples of cellular mRNAs have been described in which translational initiation occurs by internal ribosome binding, a mechanism hitherto thought to be restricted to picornaviral RNAs. New insights into the molecular mechanism of internal ribosome entry have been provided by the structural and functional analyses of both the internal ribosome entry sites and the protein factors that stimulate translation mediated by these elements.

Indexed as

Gene Expression RegulationHomeodomain ProteinsNuclear ProteinsPeptide Chain Initiation, TranslationalTranscription FactorsAnimalsAntennapedia Homeodomain ProteinBase SequenceBinding SitesDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsGene Expression Regulation, ViralMolecular Sequence DataRegulatory Sequences, Nucleic AcidRibosomesAntennapedia Homeodomain ProteinAntp protein, DrosophilaDNA-Binding ProteinsDrosophila ProteinsHomeodomain ProteinsNuclear ProteinsRNA, MessengerRNA, ViralTranscription Factors

Identifiers

PMID8504255
PMCPMC7133282
OpenAlexW2004512784

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.