Evidence map›Paper›PMID 8493094›Full record

ArticleNucleic acids research1993

Isolation of cDNA encoding a binding protein specific to 5'-phosphorylated single-stranded DNA with G-rich sequences.

T R Mizuta, Y Fukita, T Miyoshi, A Shimizu, T Honjo

Abstract read
In one paragraph

Article in Nucleic acids research, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Review
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  4. Article
  5. Review
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  7. Article
  8. Review
  9. Article
  10. Association of the mammalian helicase MAH with the pre-mRNA splicing complex.Proceedings of the National Academy of Sciences of the United States of America · 1997
    Article
  11. Article
  12. Article
  13. Clonal variants of hybridoma cells that switch isotype at a high frequency.Proceedings of the National Academy of Sciences of the United States of America · 1994
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

T R MizutaCenter for Molecular Biology and Genetics, Kyoto University, Japan.
Y Fukita
T Miyoshi
A Shimizu
T Honjo
Kyoto University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have isolated the cDNA encoding a binding protein to the sequence motif of the immunoglobulin S mu region by the southwestern method. The binding protein designated S mu bp-2 specifically binds to 5'-phosphorylated single-stranded DNA containing 5'-G and GGGG stretches. The amino acid sequence deduced from the cDNA sequence showed that the S mu bp-2 belongs to the putative helicase superfamily which is involved in replication, recombination and repair. Expression of S mu bp-2 mRNA is ubiquitous and augmented in spleen cells stimulated with lipopolysaccharide and interleukin 4 which also induce class switching. The S mu bp-2 gene is conserved among vertebrates. Possible involvement of S mu bp-2 in class switching is discussed.

Indexed as

Transcription FactorsAmino Acid SequenceAnimalsCell LineDNA-Binding ProteinsDNA, Single-StrandedGuanineHumansImmunoglobulin Switch RegionMiceMice, Inbred BALB CMolecular Sequence DataPhosphorylationRecombination, GeneticRestriction MappingSequence Homology, Amino AcidDNA-Binding ProteinsDNA, Single-StrandedGuanineIGHMBP2 protein, humanIghmbp2 protein, mouseTranscription Factors

Identifiers

PMID8493094
PMCPMC309412
OpenAlexW2028065809

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.