Trial reportEuropean journal of clinical pharmacology1993
Prevention of postoperative swelling and pain by dexamethasone after operative removal of impacted third molar teeth.
Trial report in European journal of clinical pharmacology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 90 citations in OpenAlex.
- Corticosteroids for managing acute pain subsequent to surgical extraction of mandibular third molars: A systematic review and meta-analysis.Journal of the American Dental Association (1939) · 2023Pooled it
- Comparison of dexamethasone administration through sublingual and intramuscular routes for evaluation of pain, swelling, and trismus after impacted mandibular third molar surgery-a prospective randomized controlled study.Oral and maxillofacial surgery · 2022Trial
- A triple-blind randomized clinical trial of different associations between dexamethasone and non-steroids anti-inflammatories for preemptive action in third molar extractions.Scientific reports · 2021Trial
- Effect of two routes of administration of dexamethasone on pain, edema, and trismus in impacted lower third molar surgery.Oral and maxillofacial surgery · 2011Trial
- Article
- The prophylactic effect of dexamethasone on postoperative sore throat in prone position surgery.Korean journal of anesthesiology · 2016Article
- A new technique for quantitative determination of dexamethasone in pharmaceutical and biological samples using kinetic spectrophotometric method.International journal of analytical chemistry · 2015Article
- Intravenous dexamethasone versus ketamine gargle versus intravenous dexamethasone combined with ketamine gargle for evaluation of post-operative sore throat and hoarseness: A randomized, placebo-controlled, double blind clinical trial.Advanced biomedical research · 2014Article
- Modified titanium implant as a gateway to the human body: the implant mediated drug delivery system.BioMed research international · 2014Article
- Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone.Bioinformation · 2012Article
- Effectiveness of submucosal dexamethasone to control postoperative pain & swelling in apicectomy of maxillary anterior teeth.International journal of health sciences · 2011Article
- Prophylactic effect of dexamethasone in reducing postoperative sore throat.Korean journal of anesthesiology · 2010Article
- Summary of the scientific literature for pain and anxiety control in dentistry.Anesthesia progress · 1994Article
- Efficacy of epidural local anesthetic and dexamethasone in providing postoperative analgesia: A meta-analysis.Saudi journal of anaesthesiaArticle
- Effect of pretreatment diclofenac sodium on postendodontic pain: A randomised controlled trial.Journal of conservative dentistry : JCDArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a placebo-controlled double-blind study, we examined the effect of perioperative oral administration of 6 mg dexamethasone, given once 12 h before and once 12 h after osteotomy of two impacted molar teeth, on postoperative edema, limitation of jaw opening, and intensity of postoperative pain. On the first day after surgery the difference in the increase in cheek swelling was 54.3% (P < 0.001) as measured with a tape, 46% (P < 0.001) measured with a gauge in the first molar area and 29% (P < or = 0.056) by sonographic measurement of the cheek diameter in the molar area. The limitation in the jaw opening was reduced by 17.7% (P < 0.002) after dexamethasone. Pain assessed by visual analog scale was reduced by dexamethasone by 50% (P < 0.01). The amount of analgesics required postoperatively (codeine phosphate) was reduced by 37% (P = 0.02) following dexamethasone administration. Seventy-six percent of our patients preferred perioperative medication of dexamethasone.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.