ArticleNature genetics1993
Large deletions and other gross forms of chromosome imbalance compatible with viability and fertility in the mouse.
Article in Nature genetics, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Article
- Article
- Article
- Molecular and functional mapping of the piebald deletion complex on mouse chromosome 14.Genetics · 2001Article
- Rapid generation of nested chromosomal deletions on mouse chromosome 2.Proceedings of the National Academy of Sciences of the United States of America · 2000Article
- Mouse models of genetic disease: new approaches, new paradigms.Journal of inherited metabolic disease · 1998Review
- Utility of C57BL/6J x 129/SvJae embryonic stem cells for generating chromosomal deletions: tolerance to gamma radiation and microsatellite polymorphism.Mammalian genome : official journal of the International Mammalian Genome Society · 1998Article
- X-ray-induced mutations in mouse embryonic stem cells.Proceedings of the National Academy of Sciences of the United States of America · 1998Article
- Identification of selected gamma-ray induced deficiencies in zebrafish using multiplex polymerase chain reaction.Genetics · 1996Article
- Article
- Forward and reverse genetic approaches to behavior in the mouse.Science (New York, N.Y.) · 1994Review
- Mouse rump-white mutation associated with an inversion of chromosome 5.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- Article
- Genetic imprinting in the mouse: implications for gene regulation.Journal of inherited metabolic disease · 1994Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Large deletions and other gross forms of chromosome imbalance are known in man but have rarely been found in the mouse. By screening progeny of spermatogonially irradiated male mice for a combination of runting and other phenotypic effects, we have identified animals that have large deletions comprising from 2.5-30 percent of the length of individual chromosomes, or other major chromosome changes, which are compatible with viability and fertility. Certain chromosome regions appear particularly susceptible to the generation of viable deletions and this has implications for radiation mutagenesis studies. Correlations with human deletions are also indicated.
Indexed as
Identifiers
8490655What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.