ArticleAmerican journal of human genetics1993
A somatic cell hybrid map of the long arm of human chromosome 17, containing the familial breast cancer locus (BRCA1).
Article in American journal of human genetics, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Estimation of the RNU2 macrosatellite mutation rate by BRCA1 mutation tracing.Nucleic acids research · 2014Article
- Direct visualization of the highly polymorphic RNU2 locus in proximity to the BRCA1 gene.PloS one · 2013Article
- An RNA-seq-based gene expression profiling of radiation-induced tumorigenic mammary epithelial cells.Genomics, proteomics & bioinformatics · 2012Article
- Association of PHB 1630 C>T and MTHFR 677 C>T polymorphisms with breast and ovarian cancer risk in BRCA1/2 mutation carriers: results from a multicenter study.British journal of cancer · 2012Article
- Van Buchem disease (hyperostosis corticalis generalisata) maps to chromosome 17q12-q21.American journal of human genetics · 1998Article
- Assignment of the mulibrey nanism gene to 17q by linkage and linkage-disequilibrium analysis.American journal of human genetics · 1997Article
- Irradiation and fusion gene transfer.Molecular biotechnology · 1995Review
- A radiation hybrid map of the BRCA1 region.American journal of human genetics · 1994Article
- Genetic mapping of the BRCA1 region on chromosome 17q21.American journal of human genetics · 1994Article
- Further evidence of a relationship between the retinoic acid receptor alpha locus and nonsyndromic cleft lip with or without cleft palate (CL +/- P)American journal of human genetics · 1993Article
- THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.American journal of human genetics · 1993Article
- Genetic linkage analysis in familial breast and ovarian cancer: results from 214 families. The Breast Cancer Linkage Consortium.American journal of human genetics · 1993Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe a detailed somatic cell hybrid map of human chromosome 17q11.2-q23, containing the familial breast and ovarian cancer locus (BRCA1) and highly informative closely linked markers. An X-irradiation panel of 38 hamster/human and mouse/human hybrids with fragments of chromosome 17 was generated and characterized with 22 STS markers from this chromosome. A detailed map of 61 probes onto chromosome 17q, subdividing the chromosome arm into 25 regions, was done by using a panel of hybrids with well-defined breakpoints and nine chromosome-mediated gene transfectants. Our localization of RARA, TOP2, EDH17B1 and 2, and possibly WNT3, between THRA1 and D17S181, two markers known to flank BRCA1, suggests that any of these is a potential candidate for the BRCA1 locus. The marker D17S579 (Mfd188), which is believed to be very close to BRCA1, maps closest to the EDH17B genes.
Indexed as
Identifiers
8460635PMC1682064What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.