ArticleNucleic acids research1993
The silent P mating type locus in fission yeast contains two autonomously replicating sequences.
Article in Nucleic acids research, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- The heterochromatin protein Swi6/HP1 activates replication origins at the pericentromeric region and silent mating-type locus.Nature cell biology · 2009Article
- Improved determination of plasmid copy number using quantitative real-time PCR for monitoring fermentation processes.Microbial cell factories · 2008Article
- Association of fission yeast Orp1 and Mcm6 proteins with chromosomal replication origins.Molecular and cellular biology · 1999Article
- Clustered adenine/thymine stretches are essential for function of a fission yeast replication origin.Molecular and cellular biology · 1999Article
- Article
- Localization and properties of a silencing element near the mat3-M mating-type cassette of Schizosaccharomyces pombe.Genetics · 1999Article
- A novel function of the DNA repair gene rhp6 in mating-type silencing by chromatin remodeling in fission yeast.Molecular and cellular biology · 1998Article
- Article
- Identification of a predominant replication origin in fission yeast.Nucleic acids research · 1997Article
- Genetic analysis of an ARS element from the fission yeast Schizosaccharomyces pombe.The EMBO journal · 1995Article
- Two-step activation of meiosis by the mat1 locus in Schizosaccharomyces pombe.Molecular and cellular biology · 1995Article
- Mutations in rik1, clr2, clr3 and clr4 genes asymmetrically derepress the silent mating-type loci in fission yeast.Genetics · 1994Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We show that in fission yeast two DNA fragments at the silent P mating type locus provide plasmids with the capability of autonomous replication. Bacterial vectors containing these sequences replicate in a polymeric form in fission yeast very much like plasmids with the commonly used replication sequence ars1, do. There are, however, several differences between the two new ars sequences. The percentage of cells containing the plasmid during selection, the plasmid copy number and the plasmid segregation during mitosis are all dependent on the choice of the ars sequence. A DNA fragment with ars activity from the left side of the silent P cassette represses the expression of the marker gene, ura4+, at least three hundred fold compared to plasmids containing only the other new ars sequence or only ars1. The importance of replication in this promoter independent transcriptional regulation is further substantiated by the fact that the repression is partially released in the presence of ars1 on the same plasmid.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.