ArticleThe Journal of cell biology1993
Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family.
Article in The Journal of cell biology, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 74 citations in OpenAlex.
- Myosin Class I Genes Follow a Cell Type-Specific Transcription Pattern in Human Haematopoietic Cell Lines.International journal of molecular sciences · 2026Article
- The role of motor proteins in photoreceptor protein transport and visual function.Ophthalmic genetics · 2022Article
- Tissue Architectural Cues Drive Organ Targeting of Tumor Cells in Zebrafish.Cell systems · 2019Article
- Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics.The Journal of cell biology · 2018Article
- Unconventional Myosin ID is Involved in Remyelination After Cuprizone-Induced Demyelination.Neurochemical research · 2018Article
- Knockdown of Unconventional Myosin ID Expression Induced Morphological Change in Oligodendrocytes.ASN neuro · 2016Article
- Myosin-I molecular motors at a glance.Journal of cell science · 2016Review
- Article
- Microarray-based analysis of fish egg quality after natural or controlled ovulation.BMC genomics · 2007Article
- Nuclear myosin is ubiquitously expressed and evolutionary conserved in vertebrates.Histochemistry and cell biology · 2007Article
- Mammalian class I myosin, Myo1b, is monomeric and cross-links actin filaments as determined by hydrodynamic studies and electron microscopy.Biophysical journal · 2005Article
- Calmodulin binding to recombinant myosin-1c and myosin-1c IQ peptides.BMC biochemistry · 2002Article
- Myosin-1c interacts with hair-cell receptors through its calmodulin-binding IQ domains.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2002Article
- Myr 8, a novel unconventional myosin expressed during brain development associates with the protein phosphatase catalytic subunits 1alpha and 1gamma1.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2001Article
- Association of myosin I alpha with endosomes and lysosomes in mammalian cells.Molecular biology of the cell · 1999Article
- Myogenic cells express multiple myosin isoforms.Journal of muscle research and cell motility · 1997Article
- Chicken myosin IB mRNA is highly expressed in lymphoid tissues.Journal of anatomy · 1996Article
- Brush border myosin-I truncated in the motor domain impairs the distribution and the function of endocytic compartments in an hepatoma cell line.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Molecular genetic analysis of myoF, a new Dictyostelium myosin I gene.Biophysical journal · 1995Article
- Molecular cloning of a myosin I beta isozyme that may mediate adaptation by hair cells of the bullfrog's internal ear.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A polymerase chain reaction strategy was devised to identify new members of the mammalian myosin I family of actin-based motors. Using cellular RNA from mouse granular neurons and PC12 cells, we have cloned and sequenced three 1.2-kb polymerase chain reaction products that correspond to novel mammalian myosin I genes designated MMI alpha, MMI beta, MMI gamma. The pattern of expression for each of the myosin I's is unique: messages are detected in diverse tissues including the brain, lung, kidney, liver, intestine, and adrenal gland. Overlapping clones representing full-length cDNAs for MMI alpha were obtained from mouse brain. These encode a 1,079 amino acid protein containing a myosin head, a domain with five calmodulin binding sites, and a positively charged COOH-terminal tail. In situ hybridization reveals that MMI alpha is highly expressed in virtually all neurons (but not glia) in the postnatal and adult mouse brain and in neuroblasts of the cerebellar external granular layer. Expression varies in different brain regions and undergoes developmental regulation. Myosin I's are present in diverse organisms from protozoa to vertebrates. This and the expression of three novel members of this family in brain and other mammalian tissues suggests that they may participate in critical and fundamental cellular processes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.