ArticleCalcified tissue international1993
Decrease in bone levels of 1,25-dihydroxyvitamin D in women with subcapital fracture of the femur.
Article in Calcified tissue international, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Management of osteoporosis with calcitriol in elderly Chinese patients: a systematic review.Clinical interventions in aging · 2014Pooled it
- Calcitriol. A review of its use in the treatment of postmenopausal osteoporosis and its potential in corticosteroid-induced osteoporosis.Drugs & aging · 1994Trial
- Elevated Serum 25-Hydroxyvitamin D Levels Are Associated with Improved Bone Formation and Micro-Structural Measures in Elderly Hip Fracture Patients.Journal of clinical medicine · 2019Article
- Vitamin D Activity and Metabolism in Bone.Current osteoporosis reports · 2017Review
- Autocrine and paracrine actions of vitamin d.The Clinical biochemist. Reviews · 2010Article
- Vitamin D metabolism: new concepts and clinical implications.The Clinical biochemist. Reviews · 2003Article
- Measurement of vitamin D3 metabolites in smelter workers exposed to lead and cadmium.Occupational and environmental medicine · 1998Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a previous study we were able to show that in women over the age of 45 the level of 1,25-dihydroxyvitamin D (1,25(OH)2D) in bone, but not in serum, is significantly reduced when compared with younger women. In the present study we measured the concentration of 1,25(OH)2D in sera and bones of 19 female patients with subcapital fractures of the femur, mean age 78 +/- 2 years. We were able to show that serum levels of 1,25(OH)2D were within the normal range, while bone levels were markedly reduced compared to levels in femoral bone obtained from young female cadavers or to the previously reported levels in non-osteoporotic elderly women. Thus, reduced levels of 1,25(OH)2D in bones of elderly women may lead, together with other factors, to subcapital fractures.
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Registered trials
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