Evidence map›Paper›PMID 8436252›Full record

ArticleDiabetologia1993

Plasma lipoprotein (a) concentration and phenotypes in diabetes mellitus.

A Császár, H Dieplinger, C Sandholzer, I Karádi, E Juhász, H Drexel, T Halmos, L Romics, J R Patsch, G Utermann

Open access · bronzeAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Diabetologia, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

A CsászárInstitute of Medical Biology and Human Genetics, University of Innsbruck, Austria.
H Dieplinger
C Sandholzer
I Karádi
E Juhász
H Drexel
T Halmos
L Romics
J R Patsch
G Utermann
Universität Innsbruck · ATOrszágos Korányi Tbc és Pulmonológiai Intézet · HUSemmelweis University · HUInnsbruck Medical University · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with Type 1 (insulin-dependent) and Type 2 (non-insulin-dependent) diabetes mellitus are at increased risk of developing atherosclerotic vascular diseases. A variety of lipoprotein abnormalities have been described as being associated with this increased risk. In this study, apo(a) isoform frequencies and lipoprotein(a) [Lp(a)] concentrations were determined in Type 1 and Type 2 diabetic patients in order to investigate a possible contribution of Lp(a) to the increased risk for atherosclerosis in diabetes. No significant differences in plasma Lp(a) concentrations were found in two ethnically different populations (Austrians from the province of Tyrol and Hungarians from Budapest) in either type of diabetes when compared to respective control groups (91 Type 1 and 112 Type 2 diabetic patients vs 202 control subjects in the Hungarian study and 44 Type 1 diabetic and 44 Type 2 diabetic vs 125 control subjects in the Austrian study). There were also no significant apo(a) isoform frequency differences between both patient groups and control subjects in the two study groups. These data, obtained from two large ethnically different populations, provide no evidence of a contribution of Lp(a) to the increased risk for atherosclerosis in diabetes.

Indexed as

AdultApolipoprotein A-IApolipoproteins BAustriaBlood GlucoseCholesterolCholesterol, HDLDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleFructosamineGlycated HemoglobinHexosaminesHumansHungaryLipoprotein(a)Apolipoprotein A-IApolipoproteins BBlood GlucoseCholesterolCholesterol, HDLFructosamineGlycated HemoglobinHexosaminesLipoprotein(a)Triglycerides

Identifiers

PMID8436252
OpenAlexW2033558425

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.