ArticleInfection and immunity1993
Induction of bradyzoite-specific Toxoplasma gondii antigens in gamma interferon-treated mouse macrophages.
Article in Infection and immunity, 1993. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 172 citations in OpenAlex.
- Translational control of Toxoplasma gondii differentiation.Bioscience reports · 2026Review
- Effective factors in the pathogenesis ofHeliyon · 2024Review
- ROP16-mediated activation of STAT6 enhances cyst development of type III Toxoplasma gondii in neurons.PLoS pathogens · 2023Article
- The protein phosphatase 2A holoenzyme is a key regulator of starch metabolism and bradyzoite differentiation in Toxoplasma gondii.Nature communications · 2022Article
- Restriction Checkpoint Controls Bradyzoite Development in Toxoplasma gondii.Microbiology spectrum · 2022Article
- Secreted Effectors Modulating Immune Responses toLife (Basel, Switzerland) · 2021Review
- The role of upstream open reading frames in translation regulation in the apicomplexan parasitesParasitology · 2021Review
- Depletion of Intracellular Glutamine Pools TriggersFrontiers in cellular and infection microbiology · 2021Article
- The RESTRICTION checkpoint: a window of opportunity governing developmental transitions in Toxoplasma gondii.Current opinion in microbiology · 2020Review
- The molecular biology and immune control of chronic Toxoplasma gondii infection.The Journal of clinical investigation · 2020Review
- The Bradyzoite: A Key Developmental Stage for the Persistence and Pathogenesis of Toxoplasmosis.Pathogens (Basel, Switzerland) · 2020Review
- A Comparison of Stage Conversion in the Coccidian ApicomplexansFrontiers in cellular and infection microbiology · 2020Review
- Disease Tolerance inFrontiers in cellular and infection microbiology · 2019Review
- A serological and parasitological study ofVeterinary research forum : an international quarterly journal · 2019Article
- A latent ability to persist: differentiation in Toxoplasma gondii.Cellular and molecular life sciences : CMLS · 2018Review
- Translational Control in the Latency of Apicomplexan Parasites.Trends in parasitology · 2017Review
- Impact of the host onMicrobial cell (Graz, Austria) · 2017Review
- Lactate dehydrogenase in Toxoplasma gondii controls virulence, bradyzoite differentiation, and chronic infection.PloS one · 2017Article
- ANK1 and DnaK-TPR, Two Tetratricopeptide Repeat-Containing Proteins Primarily Expressed inFrontiers in microbiology · 2017Article
- Neurons are the Primary Target Cell for the Brain-Tropic Intracellular Parasite Toxoplasma gondii.PLoS pathogens · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
By using stage-specific monoclonal antibodies, an in vitro model has been developed to analyze the kinetics of expression of stage-specific antigens during the conversion process between tachyzoites and bradyzoites of Toxoplasma gondii. Following infection of murine macrophages with bradyzoites, the expression of bradyzoite-specific antigens declined, whereas the expression of tachyzoite-specific antigens increased during the first 72 h postinfection. Conversely, in gamma interferon-treated murine macrophages infected with tachyzoites, the inhibitory effect of gamma interferon on replication of parasites was accompanied by the induction of bradyzoite-specific antigens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.